Ryan P - Search Results

1

Novel data-mining methodologies for adverse drug event discovery and analysis.

Harpaz R, DuMouchel W, Shah NH, Madigan D, Ryan P, Friedman C. Harpaz R, et al. Among authors: ryan p. Clin Pharmacol Ther. 2012 Jun;91(6):1010-21. doi: 10.1038/clpt.2012.50. Clin Pharmacol Ther. 2012. PMID: 22549283 Free PMC article. Review.

2

What can we really learn from observational studies?: the need for empirical assessment of methodology for active drug safety surveillance and comparative effectiveness research.

Madigan D, Ryan P. Madigan D, et al. Among authors: ryan p. Epidemiology. 2011 Sep;22(5):629-31. doi: 10.1097/EDE.0b013e318228ca1d. Epidemiology. 2011. PMID: 21811110 No abstract available.

3

Disproportionality methods for pharmacovigilance in longitudinal observational databases.

Zorych I, Madigan D, Ryan P, Bate A. Zorych I, et al. Among authors: ryan p. Stat Methods Med Res. 2013 Feb;22(1):39-56. doi: 10.1177/0962280211403602. Epub 2011 Aug 30. Stat Methods Med Res. 2013. PMID: 21878461

4

Empirical assessment of methods for risk identification in healthcare data: results from the experiments of the Observational Medical Outcomes Partnership.

Ryan PB, Madigan D, Stang PE, Overhage JM, Racoosin JA, Hartzema AG. Ryan PB, et al. Stat Med. 2012 Dec 30;31(30):4401-15. doi: 10.1002/sim.5620. Epub 2012 Sep 27. Stat Med. 2012. PMID: 23015364

5

Response to comment on 'empirical assessment of methods for risk identification in healthcare data'.

Ryan PB, Madigan D, Stang PE, Marc Overhage J, Racoosin JA, Hartzema AG. Ryan PB, et al. Stat Med. 2013 Mar 15;32(6):1075-7. doi: 10.1002/sim.5725. Stat Med. 2013. PMID: 23413215 No abstract available.

6

Performance of pharmacovigilance signal-detection algorithms for the FDA adverse event reporting system.

Harpaz R, DuMouchel W, LePendu P, Bauer-Mehren A, Ryan P, Shah NH. Harpaz R, et al. Among authors: ryan p. Clin Pharmacol Ther. 2013 Jun;93(6):539-46. doi: 10.1038/clpt.2013.24. Epub 2013 Feb 11. Clin Pharmacol Ther. 2013. PMID: 23571771 Free PMC article.

7

Evaluating the impact of database heterogeneity on observational study results.

Madigan D, Ryan PB, Schuemie M, Stang PE, Overhage JM, Hartzema AG, Suchard MA, DuMouchel W, Berlin JA. Madigan D, et al. Am J Epidemiol. 2013 Aug 15;178(4):645-51. doi: 10.1093/aje/kwt010. Epub 2013 May 5. Am J Epidemiol. 2013. PMID: 23648805 Free PMC article.

8

Response to "Logistic regression in signal detection: another piece added to the puzzle".

Harpaz R, DuMouchel W, LePendu P, Bauer-Mehren A, Ryan P, Shah NH. Harpaz R, et al. Among authors: ryan p. Clin Pharmacol Ther. 2013 Sep;94(3):313. doi: 10.1038/clpt.2013.125. Epub 2013 Jun 12. Clin Pharmacol Ther. 2013. PMID: 23756371 No abstract available.

9

Interpreting observational studies: why empirical calibration is needed to correct p-values.

Schuemie MJ, Ryan PB, DuMouchel W, Suchard MA, Madigan D. Schuemie MJ, et al. Stat Med. 2014 Jan 30;33(2):209-18. doi: 10.1002/sim.5925. Epub 2013 Jul 30. Stat Med. 2014. PMID: 23900808 Free PMC article.

10

Discussion: An estimate of the science-wise false discovery rate and application to the top medical literature.

Schuemie MJ, Ryan PB, Suchard MA, Shahn Z, Madigan D. Schuemie MJ, et al. Biostatistics. 2014 Jan;15(1):36-9; discussion 39-45. doi: 10.1093/biostatistics/kxt037. Epub 2013 Sep 25. Biostatistics. 2014. PMID: 24068252 Free PMC article. No abstract available.

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