Laux I - Search Results

1

Phase 1 dose-escalation trial evaluating the combination of the selective MET (mesenchymal-epithelial transition factor) inhibitor tivantinib (ARQ 197) plus erlotinib.

Goldman JW, Laux I, Chai F, Savage RE, Ferrari D, Garmey EG, Just RG, Rosen LS. Goldman JW, et al. Among authors: laux i. Cancer. 2012 Dec 1;118(23):5903-11. doi: 10.1002/cncr.27575. Epub 2012 May 17. Cancer. 2012. PMID: 22605616 Free article. Clinical Trial.

2

Phase II trial of everolimus in patients with refractory metastatic adenocarcinoma of the esophagus, gastroesophageal junction and stomach: possible role for predictive biomarkers.

Wainberg ZA, Soares HP, Patel R, DiCarlo B, Park DJ, Liem A, Wang HJ, Yonemoto L, Martinez D, Laux I, Brennan M, Hecht JR. Wainberg ZA, et al. Among authors: laux i. Cancer Chemother Pharmacol. 2015 Jul;76(1):61-7. doi: 10.1007/s00280-015-2744-5. Epub 2015 May 13. Cancer Chemother Pharmacol. 2015. PMID: 25969130 Clinical Trial.

3

Epidermal growth factor receptor dimerization status determines skin toxicity to HER-kinase targeted therapies.

Laux I, Jain A, Singh S, Agus DB. Laux I, et al. Br J Cancer. 2006 Jan 16;94(1):85-92. doi: 10.1038/sj.bjc.6602875. Br J Cancer. 2006. PMID: 16306877 Free PMC article.

4

Epithelial membrane protein-1 is a biomarker of gefitinib resistance.

Jain A, Tindell CA, Laux I, Hunter JB, Curran J, Galkin A, Afar DE, Aronson N, Shak S, Natale RB, Agus DB. Jain A, et al. Among authors: laux i. Proc Natl Acad Sci U S A. 2005 Aug 16;102(33):11858-63. doi: 10.1073/pnas.0502113102. Epub 2005 Aug 8. Proc Natl Acad Sci U S A. 2005. PMID: 16087880 Free PMC article.

5

Beta-2-microglobulin is an androgen-regulated secreted protein elevated in serum of patients with advanced prostate cancer.

Gross M, Top I, Laux I, Katz J, Curran J, Tindell C, Agus D. Gross M, et al. Among authors: laux i. Clin Cancer Res. 2007 Apr 1;13(7):1979-86. doi: 10.1158/1078-0432.CCR-06-1156. Clin Cancer Res. 2007. PMID: 17404077

6

The NF-kappa B cascade is important in Bcl-xL expression and for the anti-apoptotic effects of the CD28 receptor in primary human CD4+ lymphocytes.

Khoshnan A, Tindell C, Laux I, Bae D, Bennett B, Nel AE. Khoshnan A, et al. Among authors: laux i. J Immunol. 2000 Aug 15;165(4):1743-54. doi: 10.4049/jimmunol.165.4.1743. J Immunol. 2000. PMID: 10925251

7

Response differences between human CD4(+) and CD8(+) T-cells during CD28 costimulation: implications for immune cell-based therapies and studies related to the expansion of double-positive T-cells during aging.

Laux I, Khoshnan A, Tindell C, Bae D, Zhu X, June CH, Effros RB, Nel A. Laux I, et al. Clin Immunol. 2000 Sep;96(3):187-97. doi: 10.1006/clim.2000.4902. Clin Immunol. 2000. PMID: 10964536

8

The flotillins are integral membrane proteins in lipid rafts that contain TCR-associated signaling components: implications for T-cell activation.

Slaughter N, Laux I, Tu X, Whitelegge J, Zhu X, Effros R, Bickel P, Nel A. Slaughter N, et al. Among authors: laux i. Clin Immunol. 2003 Aug;108(2):138-51. doi: 10.1016/s1521-6616(03)00097-4. Clin Immunol. 2003. PMID: 12921760

9

Evidence that oxidative stress-induced apoptosis by menadione involves Fas-dependent and Fas-independent pathways.

Laux I, Nel A. Laux I, et al. Clin Immunol. 2001 Dec;101(3):335-44. doi: 10.1006/clim.2001.5129. Clin Immunol. 2001. PMID: 11726226

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