Meek TD - Search Results

1

On the catalytic mechanism of human ATP citrate lyase.

Fan F, Williams HJ, Boyer JG, Graham TL, Zhao H, Lehr R, Qi H, Schwartz B, Raushel FM, Meek TD. Fan F, et al. Among authors: meek td. Biochemistry. 2012 Jun 26;51(25):5198-211. doi: 10.1021/bi300611s. Epub 2012 Jun 15. Biochemistry. 2012. PMID: 22657152

2

Kinetic mechanism and rate-limiting steps of focal adhesion kinase-1.

Schneck JL, Briand J, Chen S, Lehr R, McDevitt P, Zhao B, Smallwood A, Concha N, Oza K, Kirkpatrick R, Yan K, Villa JP, Meek TD, Thrall SH. Schneck JL, et al. Among authors: meek td. Biochemistry. 2010 Aug 24;49(33):7151-63. doi: 10.1021/bi100824v. Biochemistry. 2010. PMID: 20597513

3

Understanding the origins of time-dependent inhibition by polypeptide deformylase inhibitors.

Totoritis R, Duraiswami C, Taylor AN, Kerrigan JJ, Campobasso N, Smith KJ, Ward P, King BW, Murrayz-Thompson M, Jones AD, Van Aller GS, Aubart KM, Zalacain M, Thrall SH, Meek TD, Schwartz B. Totoritis R, et al. Among authors: meek td. Biochemistry. 2011 Aug 9;50(31):6642-54. doi: 10.1021/bi200655g. Biochemistry. 2011. PMID: 21711014

4

Inhibitor binding to the Phe53Trp mutant of HIV-1 protease promotes conformational changes detectable by spectrofluorometry.

Rodríguez EJ, Debouck C, Deckman IC, Abu-Soud H, Raushel FM, Meek TD. Rodríguez EJ, et al. Among authors: meek td. Biochemistry. 1993 Apr 13;32(14):3557-63. doi: 10.1021/bi00065a006. Biochemistry. 1993. PMID: 8466899

5

Chemical mechanism of a cysteine protease, cathepsin C, as revealed by integration of both steady-state and pre-steady-state solvent kinetic isotope effects.

Schneck JL, Villa JP, McDevitt P, McQueney MS, Thrall SH, Meek TD. Schneck JL, et al. Among authors: meek td. Biochemistry. 2008 Aug 19;47(33):8697-710. doi: 10.1021/bi8007627. Epub 2008 Jul 26. Biochemistry. 2008. PMID: 18656960

6

The amino-acid substituents of dipeptide substrates of cathepsin C can determine the rate-limiting steps of catalysis.

Rubach JK, Cui G, Schneck JL, Taylor AN, Zhao B, Smallwood A, Nevins N, Wisnoski D, Thrall SH, Meek TD. Rubach JK, et al. Among authors: meek td. Biochemistry. 2012 Sep 25;51(38):7551-68. doi: 10.1021/bi300719b. Epub 2012 Sep 13. Biochemistry. 2012. PMID: 22928782

7

Kinetic and chemical mechanisms of the fabG-encoded Streptococcus pneumoniae beta-ketoacyl-ACP reductase.

Patel MP, Liu WS, West J, Tew D, Meek TD, Thrall SH. Patel MP, et al. Among authors: meek td. Biochemistry. 2005 Dec 20;44(50):16753-65. doi: 10.1021/bi050947j. Biochemistry. 2005. PMID: 16342966

8

Steady-state kinetic characterization of substrates and metal-ion specificities of the full-length and N-terminally truncated recombinant human methionine aminopeptidases (type 2).

Yang G, Kirkpatrick RB, Ho T, Zhang GF, Liang PH, Johanson KO, Casper DJ, Doyle ML, Marino JP Jr, Thompson SK, Chen W, Tew DG, Meek TD. Yang G, et al. Among authors: meek td. Biochemistry. 2001 Sep 4;40(35):10645-54. doi: 10.1021/bi010806r. Biochemistry. 2001. PMID: 11524009

9

Development of a high-throughput screen to detect inhibitors of TRPS1 sumoylation.

Brandt M, Szewczuk LM, Zhang H, Hong X, McCormick PM, Lewis TS, Graham TI, Hung ST, Harper-Jones AD, Kerrigan JJ, Wang DY, Dul E, Hou W, Ho TF, Meek TD, Cheung MH, Johanson KO, Jones CS, Schwartz B, Kumar S, Oliff AI, Kirkpatrick RB. Brandt M, et al. Among authors: meek td. Assay Drug Dev Technol. 2013 Jun;11(5):308-25. doi: 10.1089/adt.2012.501. Assay Drug Dev Technol. 2013. PMID: 23772552

10

Human immunodeficiency virus-1 protease. 2. Use of pH rate studies and solvent kinetic isotope effects to elucidate details of chemical mechanism.

Hyland LJ, Tomaszek TA Jr, Meek TD. Hyland LJ, et al. Among authors: meek td. Biochemistry. 1991 Aug 27;30(34):8454-63. doi: 10.1021/bi00098a024. Biochemistry. 1991. PMID: 1883831

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