Johnson AJ - Search Results

1

The B-cell receptor signaling pathway as a therapeutic target in CLL.

Woyach JA, Johnson AJ, Byrd JC. Woyach JA, et al. Among authors: johnson aj. Blood. 2012 Aug 9;120(6):1175-84. doi: 10.1182/blood-2012-02-362624. Epub 2012 Jun 19. Blood. 2012. PMID: 22715122 Free PMC article. Review.

2

Advances in the therapy of chronic lymphocytic leukemia.

Johnson AJ, Mone AP, Abhyankar V, Byrd JC. Johnson AJ, et al. Curr Opin Hematol. 2003 Jul;10(4):297-305. doi: 10.1097/00062752-200307000-00008. Curr Opin Hematol. 2003. PMID: 12799536 Review.

3

Hu1D10 induces apoptosis concurrent with activation of the AKT survival pathway in human chronic lymphocytic leukemia cells.

Mone AP, Huang P, Pelicano H, Cheney CM, Green JM, Tso JY, Johnson AJ, Jefferson S, Lin TS, Byrd JC. Mone AP, et al. Among authors: johnson aj. Blood. 2004 Mar 1;103(5):1846-54. doi: 10.1182/blood-2003-08-2836. Epub 2003 Nov 20. Blood. 2004. PMID: 14630799 Free article.

4

Epigenetic profiling in chronic lymphocytic leukemia reveals novel methylation targets.

Rush LJ, Raval A, Funchain P, Johnson AJ, Smith L, Lucas DM, Bembea M, Liu TH, Heerema NA, Rassenti L, Liyanarachchi S, Davuluri R, Byrd JC, Plass C. Rush LJ, et al. Among authors: johnson aj. Cancer Res. 2004 Apr 1;64(7):2424-33. doi: 10.1158/0008-5472.can-03-2870. Cancer Res. 2004. PMID: 15059895

5

A novel celecoxib derivative, OSU03012, induces cytotoxicity in primary CLL cells and transformed B-cell lymphoma cell line via a caspase- and Bcl-2-independent mechanism.

Johnson AJ, Smith LL, Zhu J, Heerema NA, Jefferson S, Mone A, Grever M, Chen CS, Byrd JC. Johnson AJ, et al. Blood. 2005 Mar 15;105(6):2504-9. doi: 10.1182/blood-2004-05-1957. Epub 2004 Sep 28. Blood. 2005. PMID: 15454489 Free article.

6

Characterization of the TCL-1 transgenic mouse as a preclinical drug development tool for human chronic lymphocytic leukemia.

Johnson AJ, Lucas DM, Muthusamy N, Smith LL, Edwards RB, De Lay MD, Croce CM, Grever MR, Byrd JC. Johnson AJ, et al. Blood. 2006 Aug 15;108(4):1334-8. doi: 10.1182/blood-2005-12-011213. Epub 2006 May 2. Blood. 2006. PMID: 16670263 Free PMC article.

7

Flavopiridol administered using a pharmacologically derived schedule is associated with marked clinical efficacy in refractory, genetically high-risk chronic lymphocytic leukemia.

Byrd JC, Lin TS, Dalton JT, Wu D, Phelps MA, Fischer B, Moran M, Blum KA, Rovin B, Brooker-McEldowney M, Broering S, Schaaf LJ, Johnson AJ, Lucas DM, Heerema NA, Lozanski G, Young DC, Suarez JR, Colevas AD, Grever MR. Byrd JC, et al. Among authors: johnson aj. Blood. 2007 Jan 15;109(2):399-404. doi: 10.1182/blood-2006-05-020735. Epub 2006 Sep 26. Blood. 2007. PMID: 17003373 Free PMC article. Clinical Trial.

8

Mcl-1 is a relevant therapeutic target in acute and chronic lymphoid malignancies: down-regulation enhances rituximab-mediated apoptosis and complement-dependent cytotoxicity.

Hussain SR, Cheney CM, Johnson AJ, Lin TS, Grever MR, Caligiuri MA, Lucas DM, Byrd JC. Hussain SR, et al. Among authors: johnson aj. Clin Cancer Res. 2007 Apr 1;13(7):2144-50. doi: 10.1158/1078-0432.CCR-06-2294. Clin Cancer Res. 2007. PMID: 17404098

9

Expression of TCL-1 as a potential prognostic factor for treatment outcome in B-cell chronic lymphocytic leukemia.

Browning RL, Geyer SM, Johnson AJ, Jelinek DF, Tschumper RC, Call TG, Shanafelt TD, Zent CS, Bone ND, Dewald GW, Lin TS, Heerema NA, Grever MR, Kay NE, Byrd JC, Lucas DM. Browning RL, et al. Among authors: johnson aj. Leuk Res. 2007 Dec;31(12):1737-40. doi: 10.1016/j.leukres.2007.05.020. Epub 2007 Jul 19. Leuk Res. 2007. PMID: 17659340 Free PMC article. Clinical Trial.

10

Novel agents and strategies for treatment of p53-defective chronic lymphocytic leukemia.

Grever MR, Lucas DM, Johnson AJ, Byrd JC. Grever MR, et al. Among authors: johnson aj. Best Pract Res Clin Haematol. 2007 Sep;20(3):545-56. doi: 10.1016/j.beha.2007.03.005. Best Pract Res Clin Haematol. 2007. PMID: 17707839

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