Large-scale characterization of cocaine addiction-like behaviors reveals that escalation of intake, aversion-resistant responding, and breaking-points are highly correlated measures of the same construct.
de Guglielmo G, Carrette L, Kallupi M, Brennan M, Boomhower B, Maturin L, Conlisk D, Sedighim S, Tieu L, Fannon MJ, Martinez AR, Velarde N, Othman D, Sichel B, Ramborger J, Lau J, Kononoff J, Kimbrough A, Simpson S, Smith LC, Shankar K, Bonnet-Zahedi S, Sneddon EA, Avelar A, Plasil SL, Mosquera J, Crook C, Chun L, Vang A, Milan KK, Schweitzer P, Lin B, Peng B, Chitre AS, Polesskaya O, Solberg Woods LC, Palmer AA, George O.
de Guglielmo G, et al. Among authors: smith lc.
Elife. 2024 Nov 1;12:RP90422. doi: 10.7554/eLife.90422.
Elife. 2024.
PMID: 39484794