Manshouri T - Search Results

1

Heterodimeric JAK-STAT activation as a mechanism of persistence to JAK2 inhibitor therapy.

Koppikar P, Bhagwat N, Kilpivaara O, Manshouri T, Adli M, Hricik T, Liu F, Saunders LM, Mullally A, Abdel-Wahab O, Leung L, Weinstein A, Marubayashi S, Goel A, Gönen M, Estrov Z, Ebert BL, Chiosis G, Nimer SD, Bernstein BE, Verstovsek S, Levine RL. Koppikar P, et al. Among authors: manshouri t. Nature. 2012 Sep 6;489(7414):155-9. doi: 10.1038/nature11303. Nature. 2012. PMID: 22820254 Free PMC article.

2

AMN107, a novel aminopyrimidine inhibitor of Bcr-Abl, has in vitro activity against imatinib-resistant chronic myeloid leukemia.

Golemovic M, Verstovsek S, Giles F, Cortes J, Manshouri T, Manley PW, Mestan J, Dugan M, Alland L, Griffin JD, Arlinghaus RB, Sun T, Kantarjian H, Beran M. Golemovic M, et al. Among authors: manshouri t. Clin Cancer Res. 2005 Jul 1;11(13):4941-7. doi: 10.1158/1078-0432.CCR-04-2601. Clin Cancer Res. 2005. PMID: 16000593

3

Activity of AMN107, a novel aminopyrimidine tyrosine kinase inhibitor, against human FIP1L1-PDGFR-alpha-expressing cells.

Verstovsek S, Giles FJ, Quintás-Cardama A, Manshouri T, Huynh L, Manley P, Cortes J, Tefferi A, Kantarjian H. Verstovsek S, et al. Among authors: manshouri t. Leuk Res. 2006 Dec;30(12):1499-505. doi: 10.1016/j.leukres.2006.03.012. Epub 2006 May 8. Leuk Res. 2006. PMID: 16682077

4

EXEL-0862, a novel tyrosine kinase inhibitor, induces apoptosis in vitro and ex vivo in human mast cells expressing the KIT D816V mutation.

Pan J, Quintás-Cardama A, Kantarjian HM, Akin C, Manshouri T, Lamb P, Cortes JE, Tefferi A, Giles FJ, Verstovsek S. Pan J, et al. Among authors: manshouri t. Blood. 2007 Jan 1;109(1):315-22. doi: 10.1182/blood-2006-04-013805. Epub 2006 Aug 15. Blood. 2007. PMID: 16912224 Free article.

5

Sensitivity of human cells bearing oncogenic mutant kit isoforms to the novel tyrosine kinase inhibitor INNO-406.

Pan J, Quintás-Cardama A, Manshouri T, Cortes J, Kantarjian H, Verstovsek S. Pan J, et al. Among authors: manshouri t. Cancer Sci. 2007 Aug;98(8):1223-5. doi: 10.1111/j.1349-7006.2007.00516.x. Epub 2007 May 22. Cancer Sci. 2007. PMID: 17517053 Free PMC article.

6

Imatinib effect on growth and signal transduction in polycythemia vera.

Gaikwad A, Verstovsek S, Yoon D, Chang KT, Manshouri T, Nussenzveig R, Cortes J, Vainchenker W, Prchal JT. Gaikwad A, et al. Among authors: manshouri t. Exp Hematol. 2007 Jun;35(6):931-8. doi: 10.1016/j.exphem.2007.03.012. Exp Hematol. 2007. PMID: 17533047

7

WP1066, a novel JAK2 inhibitor, suppresses proliferation and induces apoptosis in erythroid human cells carrying the JAK2 V617F mutation.

Verstovsek S, Manshouri T, Quintás-Cardama A, Harris D, Cortes J, Giles FJ, Kantarjian H, Priebe W, Estrov Z. Verstovsek S, et al. Among authors: manshouri t. Clin Cancer Res. 2008 Feb 1;14(3):788-96. doi: 10.1158/1078-0432.CCR-07-0524. Clin Cancer Res. 2008. PMID: 18245540

8

The JAK kinase inhibitor CP-690,550 suppresses the growth of human polycythemia vera cells carrying the JAK2V617F mutation.

Manshouri T, Quintás-Cardama A, Nussenzveig RH, Gaikwad A, Estrov Z, Prchal J, Cortes JE, Kantarjian HM, Verstovsek S. Manshouri T, et al. Cancer Sci. 2008 Jun;99(6):1265-73. doi: 10.1111/j.1349-7006.2008.00817.x. Cancer Sci. 2008. PMID: 18482053 Free PMC article.

9

Phase II study of dasatinib in Philadelphia chromosome-negative acute and chronic myeloid diseases, including systemic mastocytosis.

Verstovsek S, Tefferi A, Cortes J, O'Brien S, Garcia-Manero G, Pardanani A, Akin C, Faderl S, Manshouri T, Thomas D, Kantarjian H. Verstovsek S, et al. Among authors: manshouri t. Clin Cancer Res. 2008 Jun 15;14(12):3906-15. doi: 10.1158/1078-0432.CCR-08-0366. Clin Cancer Res. 2008. PMID: 18559612 Free PMC article. Clinical Trial.

10

The natural history and treatment outcome of blast phase BCR-ABL- myeloproliferative neoplasms.

Tam CS, Nussenzveig RM, Popat U, Bueso-Ramos CE, Thomas DA, Cortes JA, Champlin RE, Ciurea SE, Manshouri T, Pierce SM, Kantarjian HM, Verstovsek S. Tam CS, et al. Among authors: manshouri t. Blood. 2008 Sep 1;112(5):1628-37. doi: 10.1182/blood-2008-02-138230. Epub 2008 Jun 19. Blood. 2008. PMID: 18566326 Free PMC article.

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