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Applying genetics in inflammatory disease drug discovery.
Folkersen L, Biswas S, Frederiksen KS, Keller P, Fox B, Fleckner J. Folkersen L, et al. Among authors: fleckner j. Drug Discov Today. 2015 Oct;20(10):1176-81. doi: 10.1016/j.drudis.2015.05.012. Epub 2015 Jun 4. Drug Discov Today. 2015. PMID: 26050580 Free article.
Design and synthesis of novel PPARalpha/gamma/delta triple activators using a known PPARalpha/gamma dual activator as structural template.
Mogensen JP, Jeppesen L, Bury PS, Pettersson I, Fleckner J, Nehlin J, Frederiksen KS, Albrektsen T, Din N, Mortensen SB, Svensson LA, Wassermann K, Wulff EM, Ynddal L, Sauerberg P. Mogensen JP, et al. Among authors: fleckner j. Bioorg Med Chem Lett. 2003 Jan 20;13(2):257-60. doi: 10.1016/s0960-894x(02)00881-8. Bioorg Med Chem Lett. 2003. PMID: 12482434
Large dimeric ligands with favorable pharmacokinetic properties and peroxisome proliferator-activated receptor agonist activity in vitro and in vivo.
Sauerberg P, Bury PS, Mogensen JP, Deussen HJ, Pettersson I, Fleckner J, Nehlin J, Frederiksen KS, Albrektsen T, Din N, Svensson LA, Ynddal L, Wulff EM, Jeppesen L. Sauerberg P, et al. Among authors: fleckner j. J Med Chem. 2003 Nov 6;46(23):4883-94. doi: 10.1021/jm0309046. J Med Chem. 2003. PMID: 14584939
104 results