Prophylactic fresh frozen plasma may prevent development of hepatic VOD after stem cell transplantation via ADAMTS13-mediated restoration of von Willebrand factor plasma levels.
Matsumoto M, Kawa K, Uemura M, Kato S, Ishizashi H, Isonishi A, Yagi H, Park YD, Takeshima Y, Kosaka Y, Hara H, Kai S, Kanamaru A, Fukuhara S, Hino M, Sako M, Hiraoka A, Ogawa H, Hara J, Fujimura Y.
Matsumoto M, et al. Among authors: ogawa h.
Bone Marrow Transplant. 2007 Aug;40(3):251-9. doi: 10.1038/sj.bmt.1705724. Epub 2007 Jun 4.
Bone Marrow Transplant. 2007.
PMID: 17549054
Clinical Trial.