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Estrogen receptor-α is required for the osteogenic response to mechanical loading in a ligand-independent manner involving its activation function 1 but not 2.
Windahl SH, Saxon L, Börjesson AE, Lagerquist MK, Frenkel B, Henning P, Lerner UH, Galea GL, Meakin LB, Engdahl C, Sjögren K, Antal MC, Krust A, Chambon P, Lanyon LE, Price JS, Ohlsson C. Windahl SH, et al. Among authors: ohlsson c. J Bone Miner Res. 2013 Feb;28(2):291-301. doi: 10.1002/jbmr.1754. J Bone Miner Res. 2013. PMID: 22972752 Free PMC article.
Liver-derived insulin-like growth factor I (IGF-I) is the principal source of IGF-I in blood but is not required for postnatal body growth in mice.
Sjögren K, Liu JL, Blad K, Skrtic S, Vidal O, Wallenius V, LeRoith D, Törnell J, Isaksson OG, Jansson JO, Ohlsson C. Sjögren K, et al. Among authors: ohlsson c. Proc Natl Acad Sci U S A. 1999 Jun 8;96(12):7088-92. doi: 10.1073/pnas.96.12.7088. Proc Natl Acad Sci U S A. 1999. PMID: 10359843 Free PMC article.
764 results