Saxon L - Search Results

1

Estrogen receptor-α is required for the osteogenic response to mechanical loading in a ligand-independent manner involving its activation function 1 but not 2.

Windahl SH, Saxon L, Börjesson AE, Lagerquist MK, Frenkel B, Henning P, Lerner UH, Galea GL, Meakin LB, Engdahl C, Sjögren K, Antal MC, Krust A, Chambon P, Lanyon LE, Price JS, Ohlsson C. Windahl SH, et al. Among authors: saxon l. J Bone Miner Res. 2013 Feb;28(2):291-301. doi: 10.1002/jbmr.1754. J Bone Miner Res. 2013. PMID: 22972752 Free PMC article.

2

Liver-derived IGF-I regulates cortical bone mass but is dispensable for the osteogenic response to mechanical loading in female mice.

Svensson J, Windahl SH, Saxon L, Sjögren K, Koskela A, Tuukkanen J, Ohlsson C. Svensson J, et al. Among authors: saxon l. Am J Physiol Endocrinol Metab. 2016 Jul 1;311(1):E138-44. doi: 10.1152/ajpendo.00107.2016. Epub 2016 May 24. Am J Physiol Endocrinol Metab. 2016. PMID: 27221117 Free article.

3

Assessment of the in vivo adaptive response to mechanical loading.

Saxon LK, Lanyon LE. Saxon LK, et al. Methods Mol Biol. 2008;455:307-22. doi: 10.1007/978-1-59745-104-8_21. Methods Mol Biol. 2008. PMID: 18463827

4

Mechanical loading enhances the anabolic effects of intermittent parathyroid hormone (1-34) on trabecular and cortical bone in mice.

Sugiyama T, Saxon LK, Zaman G, Moustafa A, Sunters A, Price JS, Lanyon LE. Sugiyama T, et al. Bone. 2008 Aug;43(2):238-248. doi: 10.1016/j.bone.2008.04.012. Epub 2008 May 1. Bone. 2008. PMID: 18539556

5

Zaman G, Saxon LK, Sunters A, Hilton H, Underhill P, Williams D, Price JS, Lanyon LE. Zaman G, et al. Bone. 2010 Mar;46(3):628-42. doi: 10.1016/j.bone.2009.10.021. Epub 2009 Oct 24. Bone. 2010. PMID: 19857613 Free PMC article.

6

Analysis of multiple bone responses to graded strains above functional levels, and to disuse, in mice in vivo show that the human Lrp5 G171V High Bone Mass mutation increases the osteogenic response to loading but that lack of Lrp5 activity reduces it.

Saxon LK, Jackson BF, Sugiyama T, Lanyon LE, Price JS. Saxon LK, et al. Bone. 2011 Aug;49(2):184-93. doi: 10.1016/j.bone.2011.03.683. Epub 2011 Mar 16. Bone. 2011. PMID: 21419885 Free PMC article.

7

Estrogen receptors α and β have different gender-dependent effects on the adaptive responses to load bearing in cancellous and cortical bone.

Saxon LK, Galea G, Meakin L, Price J, Lanyon LE. Saxon LK, et al. Endocrinology. 2012 May;153(5):2254-66. doi: 10.1210/en.2011-1977. Epub 2012 Mar 13. Endocrinology. 2012. PMID: 22416084

8

The mouse fibula as a suitable bone for the study of functional adaptation to mechanical loading.

Moustafa A, Sugiyama T, Saxon LK, Zaman G, Sunters A, Armstrong VJ, Javaheri B, Lanyon LE, Price JS. Moustafa A, et al. Bone. 2009 May;44(5):930-5. doi: 10.1016/j.bone.2008.12.026. Epub 2009 Jan 14. Bone. 2009. PMID: 19442626 Free PMC article.

9

Wnt/beta-catenin signaling is a component of osteoblastic bone cell early responses to load-bearing and requires estrogen receptor alpha.

Armstrong VJ, Muzylak M, Sunters A, Zaman G, Saxon LK, Price JS, Lanyon LE. Armstrong VJ, et al. J Biol Chem. 2007 Jul 13;282(28):20715-27. doi: 10.1074/jbc.M703224200. Epub 2007 May 8. J Biol Chem. 2007. PMID: 17491024 Free article.

10

Zaman G, Sunters A, Galea GL, Javaheri B, Saxon LK, Moustafa A, Armstrong VJ, Price JS, Lanyon LE. Zaman G, et al. Among authors: saxon lk. J Biol Chem. 2012 Feb 3;287(6):3946-62. doi: 10.1074/jbc.M111.252742. Epub 2011 Nov 2. J Biol Chem. 2012. PMID: 22049075 Free PMC article.

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