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APP intracellular domain-WAVE1 pathway reduces amyloid-β production.
Ceglia I, Reitz C, Gresack J, Ahn JH, Bustos V, Bleck M, Zhang X, Martin G, Simon SM, Nairn AC, Greengard P, Kim Y. Ceglia I, et al. Among authors: bustos v. Nat Med. 2015 Sep;21(9):1054-9. doi: 10.1038/nm.3924. Epub 2015 Aug 17. Nat Med. 2015. PMID: 26280122 Free PMC article.
Bidirectional regulation of Aβ levels by Presenilin 1.
Bustos V, Pulina MV, Kelahmetoglu Y, Sinha SC, Gorelick FS, Flajolet M, Greengard P. Bustos V, et al. Proc Natl Acad Sci U S A. 2017 Jul 3;114(27):7142-7147. doi: 10.1073/pnas.1705235114. Epub 2017 May 22. Proc Natl Acad Sci U S A. 2017. PMID: 28533411 Free PMC article.
A Pentacyclic Triterpene from Ligustrum lucidum Targets γ-Secretase.
Luo W, Ip FCF, Fu G, Cheung K, Tian Y, Hu Y, Sinha A, Cheng EYL, Wu X, Bustos V, Greengard P, Li YM, Sinha SC, Ip NY. Luo W, et al. Among authors: bustos v. ACS Chem Neurosci. 2020 Sep 16;11(18):2827-2835. doi: 10.1021/acschemneuro.0c00389. Epub 2020 Sep 3. ACS Chem Neurosci. 2020. PMID: 32786303 Free PMC article.
Presenilin 1 phosphorylation regulates amyloid-β degradation by microglia.
Ledo JH, Liebmann T, Zhang R, Chang JC, Azevedo EP, Wong E, Silva HM, Troyanskaya OG, Bustos V, Greengard P. Ledo JH, et al. Among authors: bustos v. Mol Psychiatry. 2021 Oct;26(10):5620-5635. doi: 10.1038/s41380-020-0856-8. Epub 2020 Aug 13. Mol Psychiatry. 2021. PMID: 32792660 Free PMC article.
121 results