He G - Search Results

1

Asymmetric synthesis of a structurally and stereochemically complex spirooxindole pyran scaffold through an organocatalytic multicomponent cascade reaction.

Xie X, Peng C, He G, Leng HJ, Wang B, Huang W, Han B. Xie X, et al. Among authors: he g. Chem Commun (Camb). 2012 Nov 4;48(85):10487-9. doi: 10.1039/c2cc36011j. Chem Commun (Camb). 2012. PMID: 22983405

2

Combined structure-based pharmacophore and 3D-QSAR studies on phenylalanine series compounds as TPH1 inhibitors.

Ouyang L, He G, Huang W, Song X, Wu F, Xiang M. Ouyang L, et al. Among authors: he g. Int J Mol Sci. 2012;13(5):5348-5363. doi: 10.3390/ijms13055348. Epub 2012 May 2. Int J Mol Sci. 2012. PMID: 22754301 Free PMC article.

3

Discovery of novel focal adhesion kinase inhibitors using a hybrid protocol of virtual screening approach based on multicomplex-based pharmacophore and molecular docking.

Wu F, Xu T, He G, Ouyang L, Han B, Peng C, Song X, Xiang M. Wu F, et al. Among authors: he g. Int J Mol Sci. 2012 Nov 23;13(12):15668-78. doi: 10.3390/ijms131215668. Int J Mol Sci. 2012. PMID: 23443087 Free PMC article.

4

Synthesis of novel spirooxindolo-pyrrolidines, pyrrolizidines, and pyrrolothiazoles via a regioselective three-component [3+2] cycloaddition and their preliminary antimicrobial evaluation.

Wu G, Ouyang L, Liu J, Zeng S, Huang W, Han B, Wu F, He G, Xiang M. Wu G, et al. Among authors: he g. Mol Divers. 2013 May;17(2):271-83. doi: 10.1007/s11030-013-9432-3. Epub 2013 Mar 7. Mol Divers. 2013. PMID: 23467917

5

Molecular dynamics simulation of tryptophan hydroxylase-1: binding modes and free energy analysis to phenylalanine derivative inhibitors.

Zhong H, Huang W, He G, Peng C, Wu F, Ouyang L. Zhong H, et al. Among authors: he g. Int J Mol Sci. 2013 May 10;14(5):9947-62. doi: 10.3390/ijms14059947. Int J Mol Sci. 2013. PMID: 23665899 Free PMC article.

6

Novel hybrid virtual screening protocol based on molecular docking and structure-based pharmacophore for discovery of methionyl-tRNA synthetase inhibitors as antibacterial agents.

Liu C, He G, Jiang Q, Han B, Peng C. Liu C, et al. Among authors: he g. Int J Mol Sci. 2013 Jul 9;14(7):14225-39. doi: 10.3390/ijms140714225. Int J Mol Sci. 2013. PMID: 23839093 Free PMC article.

7

Organocatalytic tandem Morita-Baylis-Hillman-Michael reaction for asymmetric synthesis of a drug-like oxa-spirocyclic indanone scaffold.

Li X, Yang L, Peng C, Xie X, Leng HJ, Wang B, Tang ZW, He G, Ouyang L, Huang W, Han B. Li X, et al. Among authors: he g. Chem Commun (Camb). 2013 Oct 7;49(77):8692-4. doi: 10.1039/c3cc44004d. Chem Commun (Camb). 2013. PMID: 23955114

8

Diastereoselective three-component reactions of chiral nickel(II) glycinate for convenient synthesis of novel α-amino-β-substituted-γ,γ-disubstituted butyric acids.

Zhou R, Guo L, Peng C, He G, Ouyang L, Huang W. Zhou R, et al. Among authors: he g. Molecules. 2014 Jan 10;19(1):826-45. doi: 10.3390/molecules19010826. Molecules. 2014. PMID: 24434695 Free PMC article.

9

Synthesis, characterization, and evaluation of a novel amphiphilic polymer RGD-PEG-Chol for target drug delivery system.

Zeng S, Wu F, Li B, Song X, Zheng Y, He G, Peng C, Huang W. Zeng S, et al. Among authors: he g. ScientificWorldJournal. 2014 Jan 21;2014:546176. doi: 10.1155/2014/546176. eCollection 2014. ScientificWorldJournal. 2014. PMID: 24578646 Free PMC article.

10

Combining structure-based pharmacophore modeling, virtual screening, and in silico ADMET analysis to discover novel tetrahydro-quinoline based pyruvate kinase isozyme M2 activators with antitumor activity.

Chen C, Wang T, Wu F, Huang W, He G, Ouyang L, Xiang M, Peng C, Jiang Q. Chen C, et al. Among authors: he g. Drug Des Devel Ther. 2014 Sep 2;8:1195-210. doi: 10.2147/DDDT.S62921. eCollection 2014. Drug Des Devel Ther. 2014. PMID: 25214764 Free PMC article.

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