Xie X - Search Results

1

Asymmetric synthesis of a structurally and stereochemically complex spirooxindole pyran scaffold through an organocatalytic multicomponent cascade reaction.

Xie X, Peng C, He G, Leng HJ, Wang B, Huang W, Han B. Xie X, et al. Chem Commun (Camb). 2012 Nov 4;48(85):10487-9. doi: 10.1039/c2cc36011j. Chem Commun (Camb). 2012. PMID: 22983405

2

Organocatalytic tandem Morita-Baylis-Hillman-Michael reaction for asymmetric synthesis of a drug-like oxa-spirocyclic indanone scaffold.

Li X, Yang L, Peng C, Xie X, Leng HJ, Wang B, Tang ZW, He G, Ouyang L, Huang W, Han B. Li X, et al. Among authors: xie x. Chem Commun (Camb). 2013 Oct 7;49(77):8692-4. doi: 10.1039/c3cc44004d. Chem Commun (Camb). 2013. PMID: 23955114

3

Computational analysis of spiro-oxindole inhibitors of the MDM2-p53 interaction: insights and selection of novel inhibitors.

Huang W, Cai L, Chen C, Xie X, Zhao Q, Zhao X, Zhou HY, Han B, Peng C. Huang W, et al. Among authors: xie x. J Biomol Struct Dyn. 2016;34(2):341-51. doi: 10.1080/07391102.2015.1031178. Epub 2015 Jun 23. J Biomol Struct Dyn. 2016. PMID: 25808617

4

Catalytic Asymmetric Synthesis of Spiropyrazolones and their Application in Medicinal Chemistry.

Xie X, Xiang L, Peng C, Han B. Xie X, et al. Chem Rec. 2019 Nov;19(11):2209-2235. doi: 10.1002/tcr.201800199. Epub 2019 Mar 1. Chem Rec. 2019. PMID: 30821425 Review.

5

Novel HSP90-PI3K Dual Inhibitor Suppresses Melanoma Cell Proliferation by Interfering with HSP90-EGFR Interaction and Downstream Signaling Pathways.

Zhao Q, Zhu HP, Xie X, Mao Q, Liu YQ, He XH, Peng C, Jiang QL, Huang W. Zhao Q, et al. Among authors: xie x. Int J Mol Sci. 2020 Mar 7;21(5):1845. doi: 10.3390/ijms21051845. Int J Mol Sci. 2020. PMID: 32156008 Free PMC article.

6

Evodiamine alleviates lipopolysaccharide-induced pulmonary inflammation and fibrosis by activating apelin pathway.

Ye C, Zhang N, Zhao Q, Xie X, Li X, Zhu HP, Peng C, Huang W, Han B. Ye C, et al. Among authors: xie x. Phytother Res. 2021 Jun;35(6):3406-3417. doi: 10.1002/ptr.7062. Epub 2021 Mar 3. Phytother Res. 2021. PMID: 33657655

7

Recent advances on endogenous gasotransmitters in inflammatory dermatological disorders.

Wang L, Xie X, Ke B, Huang W, Jiang X, He G. Wang L, et al. Among authors: xie x. J Adv Res. 2021 Sep 1;38:261-274. doi: 10.1016/j.jare.2021.08.012. eCollection 2022 May. J Adv Res. 2021. PMID: 35572410 Free PMC article. Review.

8

Advancements in Small Molecule PROTACs Containing Indole/Spiro-fused Oxindole Scaffolds: An Emerging Degrader Targeting Cancers.

Li X, Liu Y, Huang W, Xie X, Zhu H, Peng C, Han B. Li X, et al. Among authors: xie x. Anticancer Agents Med Chem. 2023;23(10):1164-1173. doi: 10.2174/1871520622666220509175305. Anticancer Agents Med Chem. 2023. PMID: 35579130 Review.

9

Design, synthesis, and biological evaluation of novel dual inhibitors of heat shock protein 90/mammalian target of rapamycin (Hsp90/mTOR) against bladder cancer cells.

Pan Z, Chen Y, Pang H, Wang X, Zhang Y, Xie X, He G. Pan Z, et al. Among authors: xie x. Eur J Med Chem. 2022 Nov 15;242:114674. doi: 10.1016/j.ejmech.2022.114674. Epub 2022 Aug 13. Eur J Med Chem. 2022. PMID: 35987020

10

Discovery of spirooxindole-derived small-molecule compounds as novel HDAC/MDM2 dual inhibitors and investigation of their anticancer activity.

Zhao Q, Xiong SS, Chen C, Zhu HP, Xie X, Peng C, He G, Han B. Zhao Q, et al. Among authors: xie x. Front Oncol. 2022 Aug 4;12:972372. doi: 10.3389/fonc.2022.972372. eCollection 2022. Front Oncol. 2022. PMID: 35992773 Free PMC article.

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