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MR1 presents microbial vitamin B metabolites to MAIT cells.
Kjer-Nielsen L, Patel O, Corbett AJ, Le Nours J, Meehan B, Liu L, Bhati M, Chen Z, Kostenko L, Reantragoon R, Williamson NA, Purcell AW, Dudek NL, McConville MJ, O'Hair RA, Khairallah GN, Godfrey DI, Fairlie DP, Rossjohn J, McCluskey J. Kjer-Nielsen L, et al. Among authors: fairlie dp. Nature. 2012 Nov 29;491(7426):717-23. doi: 10.1038/nature11605. Epub 2012 Oct 10. Nature. 2012. PMID: 23051753
Recognition of vitamin B metabolites by mucosal-associated invariant T cells.
Patel O, Kjer-Nielsen L, Le Nours J, Eckle SB, Birkinshaw R, Beddoe T, Corbett AJ, Liu L, Miles JJ, Meehan B, Reantragoon R, Sandoval-Romero ML, Sullivan LC, Brooks AG, Chen Z, Fairlie DP, McCluskey J, Rossjohn J. Patel O, et al. Among authors: fairlie dp. Nat Commun. 2013;4:2142. doi: 10.1038/ncomms3142. Nat Commun. 2013. PMID: 23846752 Free article.
Toward drugs for protease-activated receptor 2 (PAR2).
Yau MK, Liu L, Fairlie DP. Yau MK, et al. Among authors: fairlie dp. J Med Chem. 2013 Oct 10;56(19):7477-97. doi: 10.1021/jm400638v. Epub 2013 Jul 30. J Med Chem. 2013. PMID: 23895492
Antigen-loaded MR1 tetramers define T cell receptor heterogeneity in mucosal-associated invariant T cells.
Reantragoon R, Corbett AJ, Sakala IG, Gherardin NA, Furness JB, Chen Z, Eckle SB, Uldrich AP, Birkinshaw RW, Patel O, Kostenko L, Meehan B, Kedzierska K, Liu L, Fairlie DP, Hansen TH, Godfrey DI, Rossjohn J, McCluskey J, Kjer-Nielsen L. Reantragoon R, et al. Among authors: fairlie dp. J Exp Med. 2013 Oct 21;210(11):2305-20. doi: 10.1084/jem.20130958. Epub 2013 Oct 7. J Exp Med. 2013. PMID: 24101382 Free PMC article.
T-cell activation by transitory neo-antigens derived from distinct microbial pathways.
Corbett AJ, Eckle SB, Birkinshaw RW, Liu L, Patel O, Mahony J, Chen Z, Reantragoon R, Meehan B, Cao H, Williamson NA, Strugnell RA, Van Sinderen D, Mak JY, Fairlie DP, Kjer-Nielsen L, Rossjohn J, McCluskey J. Corbett AJ, et al. Among authors: fairlie dp. Nature. 2014 May 15;509(7500):361-5. doi: 10.1038/nature13160. Epub 2014 Apr 2. Nature. 2014. PMID: 24695216
A molecular basis underpinning the T cell receptor heterogeneity of mucosal-associated invariant T cells.
Eckle SB, Birkinshaw RW, Kostenko L, Corbett AJ, McWilliam HE, Reantragoon R, Chen Z, Gherardin NA, Beddoe T, Liu L, Patel O, Meehan B, Fairlie DP, Villadangos JA, Godfrey DI, Kjer-Nielsen L, McCluskey J, Rossjohn J. Eckle SB, et al. Among authors: fairlie dp. J Exp Med. 2014 Jul 28;211(8):1585-600. doi: 10.1084/jem.20140484. Epub 2014 Jul 21. J Exp Med. 2014. PMID: 25049336 Free PMC article.
Identification of phenotypically and functionally heterogeneous mouse mucosal-associated invariant T cells using MR1 tetramers.
Rahimpour A, Koay HF, Enders A, Clanchy R, Eckle SB, Meehan B, Chen Z, Whittle B, Liu L, Fairlie DP, Goodnow CC, McCluskey J, Rossjohn J, Uldrich AP, Pellicci DG, Godfrey DI. Rahimpour A, et al. Among authors: fairlie dp. J Exp Med. 2015 Jun 29;212(7):1095-108. doi: 10.1084/jem.20142110. Epub 2015 Jun 22. J Exp Med. 2015. PMID: 26101265 Free PMC article.
Diversity of T Cells Restricted by the MHC Class I-Related Molecule MR1 Facilitates Differential Antigen Recognition.
Gherardin NA, Keller AN, Woolley RE, Le Nours J, Ritchie DS, Neeson PJ, Birkinshaw RW, Eckle SBG, Waddington JN, Liu L, Fairlie DP, Uldrich AP, Pellicci DG, McCluskey J, Godfrey DI, Rossjohn J. Gherardin NA, et al. Among authors: fairlie dp. Immunity. 2016 Jan 19;44(1):32-45. doi: 10.1016/j.immuni.2015.12.005. Epub 2016 Jan 12. Immunity. 2016. PMID: 26795251 Free article.
400 results