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Caspase-2 kills cells with extra centrosomes.
Rizzotto D, Vigorito V, Rieder P, Gallob F, Moretta GM, Soratroi C, Riley JS, Bellutti F, Veli SL, Mattivi A, Lohmüller M, Herzog S, Bornhauser BC, Jacotot ED, Villunger A, Fava LL. Rizzotto D, et al. Among authors: riley js. Sci Adv. 2024 Nov;10(44):eado6607. doi: 10.1126/sciadv.ado6607. Epub 2024 Oct 30. Sci Adv. 2024. PMID: 39475598 Free PMC article.
Rational Exploration of 2,4-Diaminopyrimidines as DHFR Inhibitors Active against Mycobacterium abscessus and Mycobacterium avium, Two Emerging Human Pathogens.
Andrade Meirelles M, Almeida VM, Sullivan JR, de Toledo I, Dos Reis CV, Cunha MR, Zigweid R, Shim A, Sankaran B, Woodward EL, Seibold S, Liu L, Mian MR, Battaile KP, Riley J, Duncan C, Simeons FRC, Ferguson L, Joji H, Read KD, Lovell S, Staker BL, Behr MA, Pilli RA, Couñago RM. Andrade Meirelles M, et al. Among authors: riley j. J Med Chem. 2024 Oct 28. doi: 10.1021/acs.jmedchem.4c01594. Online ahead of print. J Med Chem. 2024. PMID: 39468773
Cryptosporidium lysyl-tRNA synthetase inhibitors define the interplay between solubility and permeability required to achieve efficacy.
Caldwell N, Peet C, Miller P, Colon BL, Taylor MG, Cocco M, Dawson A, Lukac I, Teixeira JE, Robinson L, Frame L, Seizova S, Damerow S, Tamaki F, Post J, Riley J, Mutter N, Hanna JC, Ferguson L, Hu X, Tinti M, Forte B, Norcross NR, Campbell PS, Svensen N, Caldwell FC, Jansen C, Postis V, Read KD, Huston CD, Gilbert IH, Baragaña B, Pawlowic MC. Caldwell N, et al. Among authors: riley j. Sci Transl Med. 2024 Oct 23;16(770):eadm8631. doi: 10.1126/scitranslmed.adm8631. Epub 2024 Oct 23. Sci Transl Med. 2024. PMID: 39441903
The oocyte microenvironment is altered in adolescents compared to oocyte donors.
Gokyer D, Akinboro S, Zhou LT, Kleinhans A, Laronda MM, Duncan FE, Riley JK, Goldman KN, Babayev E. Gokyer D, et al. Among authors: riley jk. Hum Reprod Open. 2024 Aug 6;2024(3):hoae047. doi: 10.1093/hropen/hoae047. eCollection 2024. Hum Reprod Open. 2024. PMID: 39211054 Free PMC article.
Host-microbial interactions differ with age of asthma onset.
Versi A, Azim A, Ivan FX, Abdel-Aziz MI, Bates S, Riley J, Maitland-Van Der Zee AH, Dahlen SE, Djukanovic R, Chotirmall SH, Howarth P, Kermani NZ, Chung KF, Adcock IM; U-BIOPRED study group. Versi A, et al. Among authors: riley j. Eur Respir J. 2024 Sep 5;64(3):2400428. doi: 10.1183/13993003.00428-2024. Print 2024 Sep. Eur Respir J. 2024. PMID: 39190793 Free PMC article.
1,853 results