Chacko BK - Search Results

1

Controlling radicals in the powerhouse: development of MitoSOD.

Mitchell T, Chacko BK, Darley-Usmar V. Mitchell T, et al. Among authors: chacko bk. Chem Biol. 2012 Oct 26;19(10):1217-8. doi: 10.1016/j.chembiol.2012.10.004. Chem Biol. 2012. PMID: 23102214 Free PMC article.

2

Hypoxia, red blood cells, and nitrite regulate NO-dependent hypoxic vasodilation.

Crawford JH, Isbell TS, Huang Z, Shiva S, Chacko BK, Schechter AN, Darley-Usmar VM, Kerby JD, Lang JD Jr, Kraus D, Ho C, Gladwin MT, Patel RP. Crawford JH, et al. Among authors: chacko bk. Blood. 2006 Jan 15;107(2):566-74. doi: 10.1182/blood-2005-07-2668. Epub 2005 Sep 29. Blood. 2006. PMID: 16195332 Free PMC article.

3

Prevention of diabetic nephropathy in Ins2(+/)⁻(AkitaJ) mice by the mitochondria-targeted therapy MitoQ.

Chacko BK, Reily C, Srivastava A, Johnson MS, Ye Y, Ulasova E, Agarwal A, Zinn KR, Murphy MP, Kalyanaraman B, Darley-Usmar V. Chacko BK, et al. Biochem J. 2010 Nov 15;432(1):9-19. doi: 10.1042/BJ20100308. Biochem J. 2010. PMID: 20825366 Free PMC article.

4

Mitochondria-targeted ubiquinone (MitoQ) decreases ethanol-dependent micro and macro hepatosteatosis.

Chacko BK, Srivastava A, Johnson MS, Benavides GA, Chang MJ, Ye Y, Jhala N, Murphy MP, Kalyanaraman B, Darley-Usmar VM. Chacko BK, et al. Hepatology. 2011 Jul;54(1):153-63. doi: 10.1002/hep.24377. Hepatology. 2011. PMID: 21520201 Free PMC article.

5

Nitric oxide and hypoxia exacerbate alcohol-induced mitochondrial dysfunction in hepatocytes.

Zelickson BR, Benavides GA, Johnson MS, Chacko BK, Venkatraman A, Landar A, Betancourt AM, Bailey SM, Darley-Usmar VM. Zelickson BR, et al. Among authors: chacko bk. Biochim Biophys Acta. 2011 Dec;1807(12):1573-82. doi: 10.1016/j.bbabio.2011.09.011. Epub 2011 Sep 24. Biochim Biophys Acta. 2011. PMID: 21971515 Free PMC article.

6

Hemin causes mitochondrial dysfunction in endothelial cells through promoting lipid peroxidation: the protective role of autophagy.

Higdon AN, Benavides GA, Chacko BK, Ouyang X, Johnson MS, Landar A, Zhang J, Darley-Usmar VM. Higdon AN, et al. Among authors: chacko bk. Am J Physiol Heart Circ Physiol. 2012 Apr 1;302(7):H1394-409. doi: 10.1152/ajpheart.00584.2011. Epub 2012 Jan 13. Am J Physiol Heart Circ Physiol. 2012. PMID: 22245770 Free PMC article.

7

Utilization of fluorescent probes for the quantification and identification of subcellular proteomes and biological processes regulated by lipid peroxidation products.

Cummins TD, Higdon AN, Kramer PA, Chacko BK, Riggs DW, Salabei JK, Dell'Italia LJ, Zhang J, Darley-Usmar VM, Hill BG. Cummins TD, et al. Among authors: chacko bk. Free Radic Biol Med. 2013 Jun;59:56-68. doi: 10.1016/j.freeradbiomed.2012.08.014. Epub 2012 Aug 23. Free Radic Biol Med. 2013. PMID: 22954622 Free PMC article.

8

Convergent mechanisms for dysregulation of mitochondrial quality control in metabolic disease: implications for mitochondrial therapeutics.

Mitchell T, Chacko B, Ballinger SW, Bailey SM, Zhang J, Darley-Usmar V. Mitchell T, et al. Biochem Soc Trans. 2013 Feb 1;41(1):127-33. doi: 10.1042/BST20120231. Biochem Soc Trans. 2013. PMID: 23356271 Free PMC article. Review.

9

Methods for defining distinct bioenergetic profiles in platelets, lymphocytes, monocytes, and neutrophils, and the oxidative burst from human blood.

Chacko BK, Kramer PA, Ravi S, Johnson MS, Hardy RW, Ballinger SW, Darley-Usmar VM. Chacko BK, et al. Lab Invest. 2013 Jun;93(6):690-700. doi: 10.1038/labinvest.2013.53. Epub 2013 Mar 25. Lab Invest. 2013. PMID: 23528848 Free PMC article.

10

Mitochondrially targeted compounds and their impact on cellular bioenergetics.

Reily C, Mitchell T, Chacko BK, Benavides G, Murphy MP, Darley-Usmar V. Reily C, et al. Among authors: chacko bk. Redox Biol. 2013;1(1):86-93. doi: 10.1016/j.redox.2012.11.009. Redox Biol. 2013. PMID: 23667828 Free PMC article.

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