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Effects of the mu-opioid receptor antagonist GSK1521498 on hedonic and consummatory eating behaviour: a proof of mechanism study in binge-eating obese subjects.
Ziauddeen H, Chamberlain SR, Nathan PJ, Koch A, Maltby K, Bush M, Tao WX, Napolitano A, Skeggs AL, Brooke AC, Cheke L, Clayton NS, Sadaf Farooqi I, O'Rahilly S, Waterworth D, Song K, Hosking L, Richards DB, Fletcher PC, Bullmore ET. Ziauddeen H, et al. Among authors: hosking l. Mol Psychiatry. 2013 Dec;18(12):1287-93. doi: 10.1038/mp.2012.154. Epub 2012 Nov 13. Mol Psychiatry. 2013. PMID: 23147384 Free PMC article. Clinical Trial.
The effects of alcohol on the pharmacokinetics and pharmacodynamics of the selective mu-opioid receptor antagonist GSK1521498 in healthy subjects.
Ziauddeen H, Nathan PJ, Dodds C, Maltby K, Miller SR, Waterworth D, Song K, Warren L, Hosking L, Zucchetto M, Bush M, Johnson LV, Sarai B, Mogg K, Bradley BP, Richards DB, Fletcher PC, Bullmore ET. Ziauddeen H, et al. Among authors: hosking l. J Clin Pharmacol. 2013 Oct;53(10):1078-90. doi: 10.1002/jcph.110. Epub 2013 Aug 11. J Clin Pharmacol. 2013. PMID: 23934621 Free PMC article. Clinical Trial.
Opioid Antagonists and the A118G Polymorphism in the μ-Opioid Receptor Gene: Effects of GSK1521498 and Naltrexone in Healthy Drinkers Stratified by OPRM1 Genotype.
Ziauddeen H, Nestor LJ, Subramaniam N, Dodds C, Nathan PJ, Miller SR, Sarai BK, Maltby K, Fernando D, Warren L, Hosking LK, Waterworth D, Korzeniowska A, Win B, Richards DB, Vasist Johnson L, Fletcher PC, Bullmore ET. Ziauddeen H, et al. Among authors: hosking lk. Neuropsychopharmacology. 2016 Oct;41(11):2647-57. doi: 10.1038/npp.2016.60. Epub 2016 Apr 25. Neuropsychopharmacology. 2016. PMID: 27109624 Free PMC article. Clinical Trial.
Opioid Antagonists and the A118G Polymorphism in the μ-Opioid Receptor Gene: Effects of GSK1521498 and Naltrexone in Healthy Drinkers Stratified by OPRM1 Genotype.
Ziauddeen H, Nestor LJ, Subramaniam N, Dodds C, Nathan PJ, Miller SR, Sarai BK, Maltby K, Fernando D, Warren L, Hosking LK, Waterworth D, Korzeniowska A, Win B, Richards DB, Johnson LV, Fletcher PC, Bullmore ET. Ziauddeen H, et al. Among authors: hosking lk. Neuropsychopharmacology. 2018 Mar;43(4):927. doi: 10.1038/npp.2017.287. Neuropsychopharmacology. 2018. PMID: 29422496 Free PMC article.
No evidence of large genetic effects on steroid response in asthma patients.
Mosteller M, Hosking L, Murphy K, Shen J, Song K, Nelson M, Ghosh S. Mosteller M, et al. Among authors: hosking l. J Allergy Clin Immunol. 2017 Mar;139(3):797-803.e7. doi: 10.1016/j.jaci.2016.05.032. Epub 2016 Jul 5. J Allergy Clin Immunol. 2017. PMID: 27523435 Clinical Trial.
Effects of enzyme inducers efavirenz and tipranavir/ritonavir on the pharmacokinetics of the HIV integrase inhibitor dolutegravir.
Song I, Borland J, Chen S, Guta P, Lou Y, Wilfret D, Wajima T, Savina P, Peppercorn A, Castellino S, Wagner D, Hosking L, Mosteller M, Rubio JP, Piscitelli SC. Song I, et al. Among authors: hosking l. Eur J Clin Pharmacol. 2014 Oct;70(10):1173-9. doi: 10.1007/s00228-014-1732-8. Epub 2014 Aug 23. Eur J Clin Pharmacol. 2014. PMID: 25146692 Free PMC article. Clinical Trial.
A coding polymorphism in the CYSLT2 receptor with reduced affinity to LTD4 is associated with asthma.
Pillai SG, Cousens DJ, Barnes AA, Buckley PT, Chiano MN, Hosking LK, Cameron LA, Fling ME, Foley JJ, Green A, Sarau HM, Schmidt DB, Sprankle CS, Blumenthal MN, Vestbo J, Kennedy-Wilson K, Wixted WE, Wagner MJ, Anderson WH, Ignar DM; Investigators of the GAIN Network. Pillai SG, et al. Pharmacogenetics. 2004 Sep;14(9):627-33. doi: 10.1097/00008571-200409000-00007. Pharmacogenetics. 2004. PMID: 15475736
62 results