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Heterozygous deficiency of PHD2 restores tumor oxygenation and inhibits metastasis via endothelial normalization.
Mazzone M, Dettori D, de Oliveira RL, Loges S, Schmidt T, Jonckx B, Tian YM, Lanahan AA, Pollard P, de Almodovar CR, De Smet F, Vinckier S, Aragonés J, Debackere K, Luttun A, Wyns S, Jordan B, Pisacane A, Gallez B, Lampugnani MG, Dejana E, Simons M, Ratcliffe P, Maxwell P, Carmeliet P. Mazzone M, et al. Among authors: simons m. Cell. 2009 Mar 6;136(5):839-851. doi: 10.1016/j.cell.2009.01.020. Epub 2009 Feb 12. Cell. 2009. PMID: 19217150 Free PMC article.
VEGF receptor 2 endocytic trafficking regulates arterial morphogenesis.
Lanahan AA, Hermans K, Claes F, Kerley-Hamilton JS, Zhuang ZW, Giordano FJ, Carmeliet P, Simons M. Lanahan AA, et al. Among authors: simons m. Dev Cell. 2010 May 18;18(5):713-24. doi: 10.1016/j.devcel.2010.02.016. Epub 2010 May 6. Dev Cell. 2010. PMID: 20434959 Free PMC article.
FGF-dependent regulation of VEGF receptor 2 expression in mice.
Murakami M, Nguyen LT, Hatanaka K, Schachterle W, Chen PY, Zhuang ZW, Black BL, Simons M. Murakami M, et al. Among authors: simons m. J Clin Invest. 2011 Jul;121(7):2668-78. doi: 10.1172/JCI44762. J Clin Invest. 2011. PMID: 21633168 Free PMC article.
VEGF signaling inside vascular endothelial cells and beyond.
Eichmann A, Simons M. Eichmann A, et al. Among authors: simons m. Curr Opin Cell Biol. 2012 Apr;24(2):188-93. doi: 10.1016/j.ceb.2012.02.002. Epub 2012 Feb 25. Curr Opin Cell Biol. 2012. PMID: 22366328 Free PMC article. Review.
Endothelial nuclear factor-κB-dependent regulation of arteriogenesis and branching.
Tirziu D, Jaba IM, Yu P, Larrivée B, Coon BG, Cristofaro B, Zhuang ZW, Lanahan AA, Schwartz MA, Eichmann A, Simons M. Tirziu D, et al. Among authors: simons m. Circulation. 2012 Nov 27;126(22):2589-600. doi: 10.1161/CIRCULATIONAHA.112.119321. Epub 2012 Oct 22. Circulation. 2012. PMID: 23091063 Free PMC article.
1,530 results