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Drug-drug interactions between rosuvastatin and oral antidiabetic drugs occurring at the level of OATP1B1.
van de Steeg E, Greupink R, Schreurs M, Nooijen IH, Verhoeckx KC, Hanemaaijer R, Ripken D, Monshouwer M, Vlaming ML, DeGroot J, Verwei M, Russel FG, Huisman MT, Wortelboer HM. van de Steeg E, et al. Among authors: greupink r. Drug Metab Dispos. 2013 Mar;41(3):592-601. doi: 10.1124/dmd.112.049023. Epub 2012 Dec 17. Drug Metab Dispos. 2013. PMID: 23248200
Feasibility of a Pragmatic PBPK Modeling Approach: Towards Model-Informed Dosing in Pediatric Clinical Care.
van der Heijden JEM, Freriksen JJM, de Hoop-Sommen MA, van Bussel LPM, Driessen SHP, Orlebeke AEM, Verscheijden LFM, Greupink R, de Wildt SN. van der Heijden JEM, et al. Among authors: greupink r. Clin Pharmacokinet. 2022 Dec;61(12):1705-1717. doi: 10.1007/s40262-022-01181-8. Epub 2022 Nov 11. Clin Pharmacokinet. 2022. PMID: 36369327 Free PMC article.
Getting the dose right using physiologically-based pharmacokinetic modeling: dexamethasone to prevent post-extubation stridor in children as proof of concept.
van der Heijden JEM, de Hoop-Sommen M, Hoevenaars N, Freriksen JJM, Joosten K, Greupink R, de Wildt SN. van der Heijden JEM, et al. Among authors: greupink r. Front Pediatr. 2024 Jul 5;12:1416440. doi: 10.3389/fped.2024.1416440. eCollection 2024. Front Pediatr. 2024. PMID: 39035463 Free PMC article.
Towards More Robust Evaluation of the Predictive Performance of Physiologically Based Pharmacokinetic Models: Using Confidence Intervals to Support Use of Model-Informed Dosing in Clinical Care.
van Borselen MD, Sluijterman LAÆ, Greupink R, de Wildt SN. van Borselen MD, et al. Among authors: greupink r. Clin Pharmacokinet. 2024 Mar;63(3):343-355. doi: 10.1007/s40262-023-01326-3. Epub 2024 Feb 15. Clin Pharmacokinet. 2024. PMID: 38361163 Free PMC article.
Optimization of the betamethasone and dexamethasone dosing regimen during pregnancy: a combined placenta perfusion and pregnancy physiologically based pharmacokinetic modeling approach.
Van Der Heijden JEM, Van Hove H, Van Elst NM, Van Den Broek P, Van Drongelen J, Scheepers HCJ, De Wildt SN, Greupink R. Van Der Heijden JEM, et al. Among authors: greupink r. Am J Obstet Gynecol. 2024 May 17:S0002-9378(24)00594-5. doi: 10.1016/j.ajog.2024.05.012. Online ahead of print. Am J Obstet Gynecol. 2024. PMID: 38763343 Free article.
Demystifying physiologically based pharmacokinetic modelling among non-modelers towards model-informed medicine use in under-served populations.
Freriksen J, van der Heijden J, de Hoop-Sommen M, Johnson T, Yeo KR, Kerwash E, Cole S, Nooney J, Greupink R, Zhao P, de Wildt S. Freriksen J, et al. Among authors: greupink r. Gates Open Res. 2023 Oct 26;7:128. doi: 10.12688/gatesopenres.14896.1. eCollection 2023. Gates Open Res. 2023. PMID: 39035470 Free PMC article.
The impact of obesity on doravirine exposure in people with HIV.
Zino L, van Bussel LPM, Greupink R, Marneef M, Burger DM, Colbers A. Zino L, et al. Among authors: greupink r. AIDS. 2024 Feb 1;38(2):267-269. doi: 10.1097/QAD.0000000000003765. Epub 2023 Dec 20. AIDS. 2024. PMID: 38116724
73 results