Wortelboer HM - Search Results

1

Drug-drug interactions between rosuvastatin and oral antidiabetic drugs occurring at the level of OATP1B1.

van de Steeg E, Greupink R, Schreurs M, Nooijen IH, Verhoeckx KC, Hanemaaijer R, Ripken D, Monshouwer M, Vlaming ML, DeGroot J, Verwei M, Russel FG, Huisman MT, Wortelboer HM. van de Steeg E, et al. Among authors: wortelboer hm. Drug Metab Dispos. 2013 Mar;41(3):592-601. doi: 10.1124/dmd.112.049023. Epub 2012 Dec 17. Drug Metab Dispos. 2013. PMID: 23248200

2

Generation of Bayesian prediction models for OATP-mediated drug-drug interactions based on inhibition screen of OATP1B1, OATP1B1∗15 and OATP1B3.

van de Steeg E, Venhorst J, Jansen HT, Nooijen IH, DeGroot J, Wortelboer HM, Vlaming ML. van de Steeg E, et al. Among authors: wortelboer hm. Eur J Pharm Sci. 2015 Apr 5;70:29-36. doi: 10.1016/j.ejps.2015.01.004. Epub 2015 Jan 17. Eur J Pharm Sci. 2015. PMID: 25603031

3

Predicting carrier-mediated hepatic disposition of rosuvastatin in man by scaling from individual transfected cell-lines in vitro using absolute transporter protein quantification and PBPK modeling.

Bosgra S, van de Steeg E, Vlaming ML, Verhoeckx KC, Huisman MT, Verwei M, Wortelboer HM. Bosgra S, et al. Among authors: wortelboer hm. Eur J Pharm Sci. 2014 Dec 18;65:156-66. doi: 10.1016/j.ejps.2014.09.007. Epub 2014 Sep 28. Eur J Pharm Sci. 2014. PMID: 25261337

4

Interaction of digitalis-like compounds with liver uptake transporters NTCP, OATP1B1, and OATP1B3.

Gozalpour E, Greupink R, Wortelboer HM, Bilos A, Schreurs M, Russel FG, Koenderink JB. Gozalpour E, et al. Among authors: wortelboer hm. Mol Pharm. 2014 Jun 2;11(6):1844-55. doi: 10.1021/mp400699p. Epub 2014 May 6. Mol Pharm. 2014. PMID: 24754247

5

Liquid chromatography-tandem mass spectrometry analysis of free and esterified fatty acid N-acyl ethanolamines in plasma and blood cells.

Balvers MG, Wortelboer HM, Witkamp RF, Verhoeckx KC. Balvers MG, et al. Among authors: wortelboer hm. Anal Biochem. 2013 Mar 15;434(2):275-83. doi: 10.1016/j.ab.2012.11.008. Epub 2012 Nov 29. Anal Biochem. 2013. PMID: 23201387

6

Proteomic Analysis of the Developmental Trajectory of Human Hepatic Membrane Transporter Proteins in the First Three Months of Life.

Mooij MG, van de Steeg E, van Rosmalen J, Windster JD, de Koning BA, Vaes WH, van Groen BD, Tibboel D, Wortelboer HM, de Wildt SN. Mooij MG, et al. Among authors: wortelboer hm. Drug Metab Dispos. 2016 Jul;44(7):1005-13. doi: 10.1124/dmd.115.068577. Epub 2016 Apr 21. Drug Metab Dispos. 2016. PMID: 27103634

7

Regional Expression Levels of Drug Transporters and Metabolizing Enzymes along the Pig and Human Intestinal Tract and Comparison with Caco-2 Cells.

Vaessen SF, van Lipzig MM, Pieters RH, Krul CA, Wortelboer HM, van de Steeg E. Vaessen SF, et al. Among authors: wortelboer hm. Drug Metab Dispos. 2017 Apr;45(4):353-360. doi: 10.1124/dmd.116.072231. Epub 2017 Feb 2. Drug Metab Dispos. 2017. PMID: 28153842

8

Combined analysis of pharmacokinetic and efficacy data of preclinical studies with statins markedly improves translation of drug efficacy to human trials.

van de Steeg E, Kleemann R, Jansen HT, van Duyvenvoorde W, Offerman EH, Wortelboer HM, Degroot J. van de Steeg E, et al. Among authors: wortelboer hm. J Pharmacol Exp Ther. 2013 Dec;347(3):635-44. doi: 10.1124/jpet.113.208595. Epub 2013 Sep 18. J Pharmacol Exp Ther. 2013. PMID: 24049060

9

Interaction of immunosuppressive drugs with human organic anion transporter (OAT) 1 and OAT3, and multidrug resistance-associated protein (MRP) 2 and MRP4.

El-Sheikh AA, Greupink R, Wortelboer HM, van den Heuvel JJ, Schreurs M, Koenderink JB, Masereeuw R, Russel FG. El-Sheikh AA, et al. Among authors: wortelboer hm. Transl Res. 2013 Dec;162(6):398-409. doi: 10.1016/j.trsl.2013.08.003. Epub 2013 Sep 12. Transl Res. 2013. PMID: 24036158

10

A new approach to predict human intestinal absorption using porcine intestinal tissue and biorelevant matrices.

Westerhout J, van de Steeg E, Grossouw D, Zeijdner EE, Krul CA, Verwei M, Wortelboer HM. Westerhout J, et al. Among authors: wortelboer hm. Eur J Pharm Sci. 2014 Oct 15;63:167-77. doi: 10.1016/j.ejps.2014.07.003. Epub 2014 Jul 18. Eur J Pharm Sci. 2014. PMID: 25046168

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