Xu J - Search Results

1

Synthesis of spirolactone-type diterpenoid derivatives from kaurene-type oridonin with improved antiproliferative effects and their apoptosis-inducing activity in human hepatoma Bel-7402 cells.

Li D, Cai H, Jiang B, Liu G, Wang Y, Wang L, Yao H, Wu X, Sun Y, Xu J. Li D, et al. Among authors: xu j. Eur J Med Chem. 2013 Jan;59:322-8. doi: 10.1016/j.ejmech.2012.11.002. Epub 2012 Nov 21. Eur J Med Chem. 2013. PMID: 23274570

2

Synthesis and cytotoxic activity of 17-carboxylic acid modified 23-hydroxy betulinic acid ester derivatives.

Bi Y, Xu J, Wu X, Ye W, Yuan S, Zhang L. Bi Y, et al. Among authors: xu j. Bioorg Med Chem Lett. 2007 Mar 1;17(5):1475-8. doi: 10.1016/j.bmcl.2006.09.096. Epub 2006 Oct 4. Bioorg Med Chem Lett. 2007. PMID: 17275295

3

Synthesis and biological activity of 2-alkylbenzimidazoles bearing a N-phenylpyrrole moiety as novel angiotensin II AT1 receptor antagonists.

Xu JY, Zeng Y, Ran Q, Wei Z, Bi Y, He QH, Wang QJ, Hu S, Zhang J, Tang MY, Hua WY, Wu XM. Xu JY, et al. Bioorg Med Chem Lett. 2007 May 15;17(10):2921-6. doi: 10.1016/j.bmcl.2007.02.042. Epub 2007 Feb 20. Bioorg Med Chem Lett. 2007. PMID: 17412584

4

Identification of the major metabolites of 5-n-butyl-4-{4-[2-(1H-tetrazole-5-yl)-1H-pyrrol-1-yl]phenylmethyl}-2,4-dihydro-2-(2,6-dichloridephenyl)-3H-1,2,4-triazol-3-one, a new angiotensin type 1 receptor antagonist, in rat bile by HPLC-diode array detection-MS and HPLC-MS/MS.

Yan B, Wang G, Sun J, Li X, Zheng Y, Ai H, Lv H, Wu X, Xu J. Yan B, et al. Among authors: xu j. Biomed Chromatogr. 2007 Sep;21(9):912-24. doi: 10.1002/bmc.822. Biomed Chromatogr. 2007. PMID: 17428010

5

[Ca2+]i and PKC-alpha are involved in the inhibitory effects of Ib, a novel nonpeptide AngiotensinII subtype AT1 receptor antagonist, on AngiotensinII-induced vascular contraction in vitro.

Wang Y, Wang W, Wang Q, Wu J, Xu J, Wu X. Wang Y, et al. Among authors: xu j. Biochem Biophys Res Commun. 2007 Dec 7;364(1):118-23. doi: 10.1016/j.bbrc.2007.09.101. Epub 2007 Oct 1. Biochem Biophys Res Commun. 2007. PMID: 17931598

6

Characterization of angiotensin II antagonism displayed by Ib, a novel nonpeptide angiotensin AT(1) receptor antagonist.

Wu J, Wang Q, Guo J, Hu Z, Yin Z, Xu J, Wu X. Wu J, et al. Among authors: xu j. Eur J Pharmacol. 2008 Jul 28;589(1-3):220-4. doi: 10.1016/j.ejphar.2008.05.007. Epub 2008 May 20. Eur J Pharmacol. 2008. PMID: 18571160

7

Synthesis and biological evaluation of novel 1-O- and 14-O-derivatives of oridonin as potential anticancer drug candidates.

Xu J, Yang J, Ran Q, Wang L, Liu J, Wang Z, Wu X, Hua W, Yuan S, Zhang L, Shen M, Ding Y. Xu J, et al. Bioorg Med Chem Lett. 2008 Aug 15;18(16):4741-4. doi: 10.1016/j.bmcl.2008.06.097. Epub 2008 Jul 3. Bioorg Med Chem Lett. 2008. PMID: 18644718

8

PKC-dependent extracellular signal-regulated kinase 1/2 pathway is involved in the inhibition of Ib on AngiotensinII-induced proliferation of vascular smooth muscle cells.

Wang Y, Yan T, Wang Q, Wang W, Xu J, Wu X, Ji H. Wang Y, et al. Among authors: xu j. Biochem Biophys Res Commun. 2008 Oct 10;375(1):151-5. doi: 10.1016/j.bbrc.2008.07.137. Epub 2008 Aug 5. Biochem Biophys Res Commun. 2008. PMID: 18687307

9

Total synthesis and antihypertensive activity of (+/-)7,8-dihydroxy-3-methyl-isochromanone-4.

Liu J, Ren H, Xu J, Bai R, Yan Q, Huang W, Wu X, Fu J, Wang Q, Wu Q, Fu R. Liu J, et al. Among authors: xu j. Bioorg Med Chem Lett. 2009 Mar 15;19(6):1822-4. doi: 10.1016/j.bmcl.2008.12.102. Epub 2008 Dec 31. Bioorg Med Chem Lett. 2009. PMID: 19233642

10

Terpenoids. III: Synthesis and biological evaluation of 23-hydroxybetulinic acid derivatives as novel inhibitors of glycogen phosphorylase.

Zhu P, Bi Y, Xu J, Li Z, Liu J, Zhang L, Ye W, Wu X. Zhu P, et al. Among authors: xu j. Bioorg Med Chem Lett. 2009 Dec 15;19(24):6966-9. doi: 10.1016/j.bmcl.2009.10.055. Epub 2009 Nov 2. Bioorg Med Chem Lett. 2009. PMID: 19889536

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