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Functional genomics identifies type I interferon pathway as central for host defense against Candida albicans.
Smeekens SP, Ng A, Kumar V, Johnson MD, Plantinga TS, van Diemen C, Arts P, Verwiel ET, Gresnigt MS, Fransen K, van Sommeren S, Oosting M, Cheng SC, Joosten LA, Hoischen A, Kullberg BJ, Scott WK, Perfect JR, van der Meer JW, Wijmenga C, Netea MG, Xavier RJ. Smeekens SP, et al. Among authors: perfect jr. Nat Commun. 2013;4:1342. doi: 10.1038/ncomms2343. Nat Commun. 2013. PMID: 23299892 Free PMC article.
Genetic variation in the dectin-1/CARD9 recognition pathway and susceptibility to candidemia.
Rosentul DC, Plantinga TS, Oosting M, Scott WK, Velez Edwards DR, Smith PB, Alexander BD, Yang JC, Laird GM, Joosten LA, van der Meer JW, Perfect JR, Kullberg BJ, Netea MG, Johnson MD. Rosentul DC, et al. Among authors: perfect jr. J Infect Dis. 2011 Oct 1;204(7):1138-45. doi: 10.1093/infdis/jir458. J Infect Dis. 2011. PMID: 21881131 Free PMC article.
Human genetic susceptibility to Candida infections.
Plantinga TS, Johnson MD, Scott WK, Joosten LA, van der Meer JW, Perfect JR, Kullberg BJ, Netea MG. Plantinga TS, et al. Among authors: perfect jr. Med Mycol. 2012 Nov;50(8):785-94. doi: 10.3109/13693786.2012.690902. Epub 2012 Jun 4. Med Mycol. 2012. PMID: 22662758 Free PMC article. Review.
Role of autophagy genetic variants for the risk of Candida infections.
Rosentul DC, Plantinga TS, Farcas M, Oosting M, Hamza OJ, Scott WK, Alexander BD, Yang JC, Laird GM, Joosten LA, van der Meer JW, Perfect JR, Kullberg BJ, van der Ven AJ, Johnson MD, Netea MG. Rosentul DC, et al. Among authors: perfect jr. Med Mycol. 2014 May;52(4):333-41. doi: 10.1093/mmy/myt035. Epub 2014 Apr 8. Med Mycol. 2014. PMID: 24713404 Free PMC article.
Immunochip SNP array identifies novel genetic variants conferring susceptibility to candidaemia.
Kumar V, Cheng SC, Johnson MD, Smeekens SP, Wojtowicz A, Giamarellos-Bourboulis E, Karjalainen J, Franke L, Withoff S, Plantinga TS, van de Veerdonk FL, van der Meer JWM, Joosten LAB, Bochud PY, Marchetti O, Perfect JR, Xavier R, Kullberg BJ, Wijmenga C, Netea MG. Kumar V, et al. Among authors: perfect jr. Nat Commun. 2014 Sep 8;5:4675. doi: 10.1038/ncomms5675. Nat Commun. 2014. PMID: 25197941 Free PMC article.
The RIG-I-like helicase receptor MDA5 (IFIH1) is involved in the host defense against Candida infections.
Jaeger M, van der Lee R, Cheng SC, Johnson MD, Kumar V, Ng A, Plantinga TS, Smeekens SP, Oosting M, Wang X, Barchet W, Fitzgerald K, Joosten LAB, Perfect JR, Wijmenga C, van de Veerdonk FL, Huynen MA, Xavier RJ, Kullberg BJ, Netea MG. Jaeger M, et al. Among authors: perfect jr. Eur J Clin Microbiol Infect Dis. 2015 May;34(5):963-974. doi: 10.1007/s10096-014-2309-2. Epub 2015 Jan 13. Eur J Clin Microbiol Infect Dis. 2015. PMID: 25579795 Free PMC article.
An integrative genomics approach identifies novel pathways that influence candidaemia susceptibility.
Matzaraki V, Gresnigt MS, Jaeger M, Ricaño-Ponce I, Johnson MD, Oosting M, Franke L, Withoff S, Perfect JR, Joosten LAB, Kullberg BJ, van de Veerdonk FL, Jonkers I, Li Y, Wijmenga C, Netea MG, Kumar V. Matzaraki V, et al. Among authors: perfect jr. PLoS One. 2017 Jul 20;12(7):e0180824. doi: 10.1371/journal.pone.0180824. eCollection 2017. PLoS One. 2017. PMID: 28727728 Free PMC article.
A Genome-Wide Functional Genomics Approach Identifies Susceptibility Pathways to Fungal Bloodstream Infection in Humans.
Jaeger M, Matzaraki V, Aguirre-Gamboa R, Gresnigt MS, Chu X, Johnson MD, Oosting M, Smeekens SP, Withoff S, Jonkers I, Perfect JR, van de Veerdonk FL, Kullberg BJ, Joosten LAB, Li Y, Wijmenga C, Netea MG, Kumar V. Jaeger M, et al. Among authors: perfect jr. J Infect Dis. 2019 Jul 31;220(5):862-872. doi: 10.1093/infdis/jiz206. J Infect Dis. 2019. PMID: 31241743 Free PMC article.
Autophagy is redundant for the host defense against systemic Candida albicans infections.
Smeekens SP, Malireddi RK, Plantinga TS, Buffen K, Oosting M, Joosten LA, Kullberg BJ, Perfect JR, Scott WK, van de Veerdonk FL, Xavier RJ, van de Vosse E, Kanneganti TD, Johnson MD, Netea MG. Smeekens SP, et al. Among authors: perfect jr. Eur J Clin Microbiol Infect Dis. 2014 May;33(5):711-22. doi: 10.1007/s10096-013-2002-x. Epub 2013 Nov 8. Eur J Clin Microbiol Infect Dis. 2014. PMID: 24202731
Toll-like receptor 1 polymorphisms increase susceptibility to candidemia.
Plantinga TS, Johnson MD, Scott WK, van de Vosse E, Velez Edwards DR, Smith PB, Alexander BD, Yang JC, Kremer D, Laird GM, Oosting M, Joosten LA, van der Meer JW, van Dissel JT, Walsh TJ, Perfect JR, Kullberg BJ, Netea MG. Plantinga TS, et al. Among authors: perfect jr. J Infect Dis. 2012 Mar 15;205(6):934-43. doi: 10.1093/infdis/jir867. Epub 2012 Feb 1. J Infect Dis. 2012. PMID: 22301633 Free PMC article.
520 results