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Design, synthesis, and pharmacological characterization of N- and O-substituted 5,6,7,8-tetrahydro-4H-isoxazolo[4,5-d]azepin-3-ol analogues: novel 5-HT(2A)/5-HT(2C) receptor agonists with pro-cognitive properties.
Jensen AA, Plath N, Pedersen MH, Isberg V, Krall J, Wellendorph P, Stensbøl TB, Gloriam DE, Krogsgaard-Larsen P, Frølund B. Jensen AA, et al. Among authors: pedersen mh. J Med Chem. 2013 Feb 14;56(3):1211-27. doi: 10.1021/jm301656h. Epub 2013 Jan 17. J Med Chem. 2013. PMID: 23301527
Design, synthesis, and in vitro pharmacology of new radiolabeled gamma-hydroxybutyric acid analogues including photolabile analogues with irreversible binding to the high-affinity gamma-hydroxybutyric acid binding sites.
Sabbatini P, Wellendorph P, Høg S, Pedersen MH, Bräuner-Osborne H, Martiny L, Frølund B, Clausen RP. Sabbatini P, et al. Among authors: pedersen mh. J Med Chem. 2010 Sep 9;53(17):6506-10. doi: 10.1021/jm1006325. J Med Chem. 2010. PMID: 20715819
Bioavailability Studies and in vitro Profiling of the Selective Excitatory Amino Acid Transporter Subtype 1 (EAAT1) Inhibitor UCPH-102.
Haym I, Huynh TH, Hansen SW, Pedersen MH, Ruiz JA, Erichsen MN, Gynther M, Bjørn-Yoshimoto WE, Abrahamsen B, Bastlund JF, Bundgaard C, Eriksen AL, Jensen AA, Bunch L. Haym I, et al. Among authors: pedersen mh. ChemMedChem. 2016 Feb 17;11(4):403-19. doi: 10.1002/cmdc.201500527. Epub 2016 Jan 21. ChemMedChem. 2016. PMID: 26797816 Free article.
Engineered α4β2 nicotinic acetylcholine receptors as models for measuring agonist binding and effect at the orthosteric low-affinity α4-α4 interface.
Ahring PK, Olsen JA, Nielsen EØ, Peters D, Pedersen MH, Rohde LA, Kastrup JS, Shahsavar A, Indurthi DC, Chebib M, Gajhede M, Balle T. Ahring PK, et al. Among authors: pedersen mh. Neuropharmacology. 2015 May;92:135-45. doi: 10.1016/j.neuropharm.2014.12.035. Epub 2015 Jan 13. Neuropharmacology. 2015. PMID: 25595102
Correction: Impact of membrane lipid polyunsaturation on dopamine D2 receptor ligand binding and signaling.
Jobin ML, De Smedt-Peyrusse V, Ducrocq F, Baccouch R, Oummadi A, Pedersen MH, Medel-Lacruz B, Angelo MF, Villette S, Van Delft P, Fouillen L, Mongrand S, Selent J, Tolentino-Cortez T, Barreda-Gómez G, Grégoire S, Masson E, Durroux T, Javitch JA, Guixà-González R, Alves ID, Trifilieff P. Jobin ML, et al. Among authors: pedersen mh. Mol Psychiatry. 2023 May;28(5):2171. doi: 10.1038/s41380-023-02196-8. Mol Psychiatry. 2023. PMID: 37550407 No abstract available.
94 results