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871 results

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How insulin engages its primary binding site on the insulin receptor.
Menting JG, Whittaker J, Margetts MB, Whittaker LJ, Kong GK, Smith BJ, Watson CJ, Záková L, Kletvíková E, Jiráček J, Chan SJ, Steiner DF, Dodson GG, Brzozowski AM, Weiss MA, Ward CW, Lawrence MC. Menting JG, et al. Among authors: watson cj. Nature. 2013 Jan 10;493(7431):241-5. doi: 10.1038/nature11781. Nature. 2013. PMID: 23302862 Free PMC article.
Human insulin analogues modified at the B26 site reveal a hormone conformation that is undetected in the receptor complex.
Záková L, Kletvíková E, Lepšík M, Collinsová M, Watson CJ, Turkenburg JP, Jiráček J, Brzozowski AM. Záková L, et al. Among authors: watson cj. Acta Crystallogr D Biol Crystallogr. 2014 Oct;70(Pt 10):2765-74. doi: 10.1107/S1399004714017775. Epub 2014 Sep 27. Acta Crystallogr D Biol Crystallogr. 2014. PMID: 25286859 Free PMC article.
Rational steering of insulin binding specificity by intra-chain chemical crosslinking.
Viková J, Collinsová M, Kletvíková E, Buděšínský M, Kaplan V, Žáková L, Veverka V, Hexnerová R, Tarazona Aviñó RJ, Straková J, Selicharová I, Vaněk V, Wright DW, Watson CJ, Turkenburg JP, Brzozowski AM, Jiráček J. Viková J, et al. Among authors: watson cj. Sci Rep. 2016 Jan 21;6:19431. doi: 10.1038/srep19431. Sci Rep. 2016. PMID: 26792393 Free PMC article.
Expanding Opportunities for Living Donation: Recommendations From the 2023 Santander Summit to Ensure Donor Protections, Informed Decision Making, and Equitable Access.
Lentine KL, Waterman AD, Cooper M, Nagral S, Gardiner D, Spiro M, Rela M, Danovitch G, Watson CJE, Thomson D, Van Assche K, Torres M, Domínguez-Gil B, Delmonico FL; Donation Workgroup Collaborators. Lentine KL, et al. Among authors: watson cje. Transplantation. 2024 Oct 22. doi: 10.1097/TP.0000000000005124. Online ahead of print. Transplantation. 2024. PMID: 39437374
SIGNET: protocol for a multicentre, single-blind prospective, group sequential, randomised controlled trial to evaluate the benefits of a single dose of simvastatin given to potential organ donors declared dead by neurological criteria on outcomes in organ recipients.
Evans A, Mawson P, Thomas H, Keen K, Watson CJ, McAuley DF, MacGowan GA, Sheerin NS, Fisher A, Shaw J, Yates H, Fallow A, Kounali D, Banks J, Stevens M, Paul R, Hodge R, Lawson E, Harvey D, Dark J. Evans A, et al. Among authors: watson cj. BMJ Open. 2024 Sep 18;14(9):e086352. doi: 10.1136/bmjopen-2024-086352. BMJ Open. 2024. PMID: 39299790 Free PMC article.
871 results