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A host transcriptional signature for presymptomatic detection of infection in humans exposed to influenza H1N1 or H3N2.
Woods CW, McClain MT, Chen M, Zaas AK, Nicholson BP, Varkey J, Veldman T, Kingsmore SF, Huang Y, Lambkin-Williams R, Gilbert AG, Hero AO 3rd, Ramsburg E, Glickman S, Lucas JE, Carin L, Ginsburg GS. Woods CW, et al. PLoS One. 2013;8(1):e52198. doi: 10.1371/journal.pone.0052198. Epub 2013 Jan 9. PLoS One. 2013. PMID: 23326326 Free PMC article.
A Genomic Signature of Influenza Infection Shows Potential for Presymptomatic Detection, Guiding Early Therapy, and Monitoring Clinical Responses.
McClain MT, Nicholson BP, Park LP, Liu TY, Hero AO 3rd, Tsalik EL, Zaas AK, Veldman T, Hudson LL, Lambkin-Williams R, Gilbert A, Burke T, Nichols M, Ginsburg GS, Woods CW. McClain MT, et al. Open Forum Infect Dis. 2016 Jan 19;3(1):ofw007. doi: 10.1093/ofid/ofw007. eCollection 2016 Jan. Open Forum Infect Dis. 2016. PMID: 26933666 Free PMC article.
Nasopharyngeal Protein Biomarkers of Acute Respiratory Virus Infection.
Burke TW, Henao R, Soderblom E, Tsalik EL, Thompson JW, McClain MT, Nichols M, Nicholson BP, Veldman T, Lucas JE, Moseley MA, Turner RB, Lambkin-Williams R, Hero AO 3rd, Woods CW, Ginsburg GS. Burke TW, et al. EBioMedicine. 2017 Mar;17:172-181. doi: 10.1016/j.ebiom.2017.02.015. Epub 2017 Feb 21. EBioMedicine. 2017. PMID: 28238698 Free PMC article.
The effective rate of influenza reassortment is limited during human infection.
Sobel Leonard A, McClain MT, Smith GJ, Wentworth DE, Halpin RA, Lin X, Ransier A, Stockwell TB, Das SR, Gilbert AS, Lambkin-Williams R, Ginsburg GS, Woods CW, Koelle K, Illingworth CJ. Sobel Leonard A, et al. PLoS Pathog. 2017 Feb 7;13(2):e1006203. doi: 10.1371/journal.ppat.1006203. eCollection 2017 Feb. PLoS Pathog. 2017. PMID: 28170438 Free PMC article.
Deep Sequencing of Influenza A Virus from a Human Challenge Study Reveals a Selective Bottleneck and Only Limited Intrahost Genetic Diversification.
Sobel Leonard A, McClain MT, Smith GJ, Wentworth DE, Halpin RA, Lin X, Ransier A, Stockwell TB, Das SR, Gilbert AS, Lambkin-Williams R, Ginsburg GS, Woods CW, Koelle K. Sobel Leonard A, et al. J Virol. 2016 Nov 28;90(24):11247-11258. doi: 10.1128/JVI.01657-16. Print 2016 Dec 15. J Virol. 2016. PMID: 27707932 Free PMC article.
Accelerating Influenza Research: Vaccines, Antivirals, Immunomodulators and Monoclonal Antibodies. The Manufacture of a New Wild-Type H3N2 Virus for the Human Viral Challenge Model.
Fullen DJ, Noulin N, Catchpole A, Fathi H, Murray EJ, Mann A, Eze K, Balaratnam G, Borley DW, Gilbert A, Lambkin-Williams R. Fullen DJ, et al. PLoS One. 2016 Jan 13;11(1):e0145902. doi: 10.1371/journal.pone.0145902. eCollection 2016. PLoS One. 2016. PMID: 26761707 Free PMC article. Clinical Trial.
42 results