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iRHOM2 is a critical pathogenic mediator of inflammatory arthritis.
Issuree PD, Maretzky T, McIlwain DR, Monette S, Qing X, Lang PA, Swendeman SL, Park-Min KH, Binder N, Kalliolias GD, Yarilina A, Horiuchi K, Ivashkiv LB, Mak TW, Salmon JE, Blobel CP. Issuree PD, et al. Among authors: blobel cp. J Clin Invest. 2013 Feb;123(2):928-32. doi: 10.1172/JCI66168. Epub 2013 Jan 25. J Clin Invest. 2013. PMID: 23348744 Free PMC article.
ADAM10 is a principal 'sheddase' of the low-affinity immunoglobulin E receptor CD23.
Weskamp G, Ford JW, Sturgill J, Martin S, Docherty AJ, Swendeman S, Broadway N, Hartmann D, Saftig P, Umland S, Sehara-Fujisawa A, Black RA, Ludwig A, Becherer JD, Conrad DH, Blobel CP. Weskamp G, et al. Among authors: blobel cp. Nat Immunol. 2006 Dec;7(12):1293-8. doi: 10.1038/ni1399. Epub 2006 Oct 29. Nat Immunol. 2006. PMID: 17072319
146 results