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Synthesis, in vitro and in vivo evaluation of [O-methyl-11C] 2-{4-[4-(3-methoxyphenyl)piperazin-1-yl]-butyl}-4-methyl-2H-[1,2,4]-triazine-3,5-dione: a novel agonist 5-HT1A receptor PET ligand.
Prabhakaran J, Parsey RV, Majo VJ, Hsiung SC, Milak MS, Tamir H, Simpson NR, Van Heertum RL, Mann JJ, Dileep Kumar JS. Prabhakaran J, et al. Among authors: milak ms. Bioorg Med Chem Lett. 2006 Apr 15;16(8):2101-4. doi: 10.1016/j.bmcl.2006.01.052. Epub 2006 Feb 3. Bioorg Med Chem Lett. 2006. PMID: 16458504
Synthesis and in vivo evaluation of a novel 5-HT1A receptor agonist radioligand [O-methyl- 11C]2-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl)-4-methyl-1,2,4-triazine-3,5(2H,4H)dione in nonhuman primates.
Kumar JS, Prabhakaran J, Majo VJ, Milak MS, Hsiung SC, Tamir H, Simpson NR, Van Heertum RL, Mann JJ, Parsey RV. Kumar JS, et al. Among authors: milak ms. Eur J Nucl Med Mol Imaging. 2007 Jul;34(7):1050-60. doi: 10.1007/s00259-006-0324-y. Epub 2007 Jan 13. Eur J Nucl Med Mol Imaging. 2007. PMID: 17221184
Positron emission tomography study of regional brain metabolic responses to a serotonergic challenge in major depressive disorder with and without comorbid lifetime alcohol dependence.
Sher L, Milak MS, Parsey RV, Carballo JJ, Cooper TB, Malone KM, Oquendo MA, Mann JJ. Sher L, et al. Among authors: milak ms. Eur Neuropsychopharmacol. 2007 Sep;17(9):608-15. doi: 10.1016/j.euroneuro.2007.03.007. Epub 2007 May 2. Eur Neuropsychopharmacol. 2007. PMID: 17478085 Free PMC article.
44 results