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Pharmacokinetics of darunavir in fixed-dose combination with cobicistat compared with coadministration of darunavir and ritonavir as single agents in healthy volunteers.
Kakuda TN, Opsomer M, Timmers M, Iterbeke K, Van De Casteele T, Hillewaert V, Petrovic R, Hoetelmans RM. Kakuda TN, et al. Among authors: hoetelmans rm. J Clin Pharmacol. 2014 Aug;54(8):949-57. doi: 10.1002/jcph.290. Epub 2014 Mar 26. J Clin Pharmacol. 2014. PMID: 24644095 Clinical Trial.
Single- and multiple-dose pharmacokinetics and safety of pimodivir, a novel, non-nucleoside polymerase basic protein 2 subunit inhibitor of the influenza A virus polymerase complex, and interaction with oseltamivir: a Phase 1 open-label study in healthy volunteers.
Deleu S, Kakuda TN, Spittaels K, Vercauteren JJ, Hillewaert V, Lwin A, Leopold L, Hoetelmans RMW. Deleu S, et al. Among authors: hoetelmans rmw. Br J Clin Pharmacol. 2018 Nov;84(11):2663-2672. doi: 10.1111/bcp.13733. Epub 2018 Sep 14. Br J Clin Pharmacol. 2018. PMID: 30098042 Free PMC article. Clinical Trial.
Pharmacokinetic and pharmacodynamic study of the concomitant administration of methadone and TMC125 in HIV-negative volunteers.
Schöller-Gyüre M, van den Brink W, Kakuda TN, Woodfall B, De Smedt G, Vanaken H, Stevens T, Peeters M, Vandermeulen K, Hoetelmans RM. Schöller-Gyüre M, et al. Among authors: hoetelmans rm. J Clin Pharmacol. 2008 Mar;48(3):322-9. doi: 10.1177/0091270007310387. Epub 2008 Jan 14. J Clin Pharmacol. 2008. PMID: 18195053 Clinical Trial.
A pharmacokinetic study of etravirine (TMC125) co-administered with ranitidine and omeprazole in HIV-negative volunteers.
Schöller-Gyüre M, Kakuda TN, De Smedt G, Vanaken H, Bouche MP, Peeters M, Woodfall B, Hoetelmans RM. Schöller-Gyüre M, et al. Among authors: hoetelmans rm. Br J Clin Pharmacol. 2008 Oct;66(4):508-16. doi: 10.1111/j.1365-2125.2008.03214.x. Epub 2008 Apr 25. Br J Clin Pharmacol. 2008. PMID: 18492125 Free PMC article. Clinical Trial.
142 results