Helleday T - Search Results

1

Replication stress links structural and numerical cancer chromosomal instability.

Burrell RA, McClelland SE, Endesfelder D, Groth P, Weller MC, Shaikh N, Domingo E, Kanu N, Dewhurst SM, Gronroos E, Chew SK, Rowan AJ, Schenk A, Sheffer M, Howell M, Kschischo M, Behrens A, Helleday T, Bartek J, Tomlinson IP, Swanton C. Burrell RA, et al. Among authors: helleday t. Nature. 2013 Feb 28;494(7438):492-496. doi: 10.1038/nature11935. Nature. 2013. PMID: 23446422 Free PMC article.

2

The cell-cycle checkpoint kinase Chk1 is required for mammalian homologous recombination repair.

Sørensen CS, Hansen LT, Dziegielewski J, Syljuåsen RG, Lundin C, Bartek J, Helleday T. Sørensen CS, et al. Among authors: helleday t. Nat Cell Biol. 2005 Feb;7(2):195-201. doi: 10.1038/ncb1212. Epub 2005 Jan 23. Nat Cell Biol. 2005. PMID: 15665856

3

Inhibition of human Chk1 causes increased initiation of DNA replication, phosphorylation of ATR targets, and DNA breakage.

Syljuåsen RG, Sørensen CS, Hansen LT, Fugger K, Lundin C, Johansson F, Helleday T, Sehested M, Lukas J, Bartek J. Syljuåsen RG, et al. Among authors: helleday t. Mol Cell Biol. 2005 May;25(9):3553-62. doi: 10.1128/MCB.25.9.3553-3562.2005. Mol Cell Biol. 2005. PMID: 15831461 Free PMC article.

4

Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints.

Bartkova J, Rezaei N, Liontos M, Karakaidos P, Kletsas D, Issaeva N, Vassiliou LV, Kolettas E, Niforou K, Zoumpourlis VC, Takaoka M, Nakagawa H, Tort F, Fugger K, Johansson F, Sehested M, Andersen CL, Dyrskjot L, Ørntoft T, Lukas J, Kittas C, Helleday T, Halazonetis TD, Bartek J, Gorgoulis VG. Bartkova J, et al. Among authors: helleday t. Nature. 2006 Nov 30;444(7119):633-7. doi: 10.1038/nature05268. Nature. 2006. PMID: 17136093

5

RPA mediates recombination repair during replication stress and is displaced from DNA by checkpoint signalling in human cells.

Sleeth KM, Sørensen CS, Issaeva N, Dziegielewski J, Bartek J, Helleday T. Sleeth KM, et al. Among authors: helleday t. J Mol Biol. 2007 Oct 12;373(1):38-47. doi: 10.1016/j.jmb.2007.07.068. Epub 2007 Aug 15. J Mol Biol. 2007. PMID: 17765923

6

Regulators of cyclin-dependent kinases are crucial for maintaining genome integrity in S phase.

Beck H, Nähse V, Larsen MS, Groth P, Clancy T, Lees M, Jørgensen M, Helleday T, Syljuåsen RG, Sørensen CS. Beck H, et al. Among authors: helleday t. J Cell Biol. 2010 Mar 8;188(5):629-38. doi: 10.1083/jcb.200905059. Epub 2010 Mar 1. J Cell Biol. 2010. PMID: 20194642 Free PMC article.

7

Methylated DNA causes a physical block to replication forks independently of damage signalling, O(6)-methylguanine or DNA single-strand breaks and results in DNA damage.

Groth P, Ausländer S, Majumder MM, Schultz N, Johansson F, Petermann E, Helleday T. Groth P, et al. Among authors: helleday t. J Mol Biol. 2010 Sep 10;402(1):70-82. doi: 10.1016/j.jmb.2010.07.010. Epub 2010 Jul 17. J Mol Biol. 2010. PMID: 20643142

8

UV stalled replication forks restart by re-priming in human fibroblasts.

Elvers I, Johansson F, Groth P, Erixon K, Helleday T. Elvers I, et al. Among authors: helleday t. Nucleic Acids Res. 2011 Sep 1;39(16):7049-57. doi: 10.1093/nar/gkr420. Epub 2011 Jun 6. Nucleic Acids Res. 2011. PMID: 21646340 Free PMC article.

9

Homologous recombination repairs secondary replication induced DNA double-strand breaks after ionizing radiation.

Groth P, Orta ML, Elvers I, Majumder MM, Lagerqvist A, Helleday T. Groth P, et al. Among authors: helleday t. Nucleic Acids Res. 2012 Aug;40(14):6585-94. doi: 10.1093/nar/gks315. Epub 2012 Apr 13. Nucleic Acids Res. 2012. PMID: 22505579 Free PMC article.

10

PrimPol breaks replication barriers.

Helleday T. Helleday T. Nat Struct Mol Biol. 2013 Dec;20(12):1348-50. doi: 10.1038/nsmb.2727. Nat Struct Mol Biol. 2013. PMID: 24304914

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

295 results

Search Page

Filters