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TGR5 signalling inhibits the production of pro-inflammatory cytokines by in vitro differentiated inflammatory and intestinal macrophages in Crohn's disease.
Yoneno K, Hisamatsu T, Shimamura K, Kamada N, Ichikawa R, Kitazume MT, Mori M, Uo M, Namikawa Y, Matsuoka K, Sato T, Koganei K, Sugita A, Kanai T, Hibi T. Yoneno K, et al. Among authors: shimamura k. Immunology. 2013 May;139(1):19-29. doi: 10.1111/imm.12045. Immunology. 2013. PMID: 23566200 Free PMC article. Clinical Trial.
Activated hepatic stellate cells mediate the differentiation of macrophages.
Chang J, Hisamatsu T, Shimamura K, Yoneno K, Adachi M, Naruse H, Igarashi T, Higuchi H, Matsuoka K, Kitazume MT, Ando S, Kamada N, Kanai T, Hibi T. Chang J, et al. Among authors: shimamura k. Hepatol Res. 2013 Jun;43(6):658-69. doi: 10.1111/j.1872-034X.2012.01111.x. Epub 2012 Oct 29. Hepatol Res. 2013. PMID: 23107150
β-(1,3)-Glucan derived from Candida albicans induces inflammatory cytokines from macrophages and lamina propria mononuclear cells derived from patients with Crohn's disease.
Mori K, Naganuma M, Mizuno S, Suzuki H, Kitazume MT, Shimamura K, Chiba S, Sugita A, Matsuoka K, Hisamatsu T, Kanai T. Mori K, et al. Among authors: shimamura k. Intest Res. 2018 Jul;16(3):384-392. doi: 10.5217/ir.2018.16.3.384. Epub 2018 Jul 27. Intest Res. 2018. PMID: 30090037 Free PMC article.
A high-cholesterol diet exacerbates liver fibrosis in mice via accumulation of free cholesterol in hepatic stellate cells.
Teratani T, Tomita K, Suzuki T, Oshikawa T, Yokoyama H, Shimamura K, Tominaga S, Hiroi S, Irie R, Okada Y, Kurihara C, Ebinuma H, Saito H, Hokari R, Sugiyama K, Kanai T, Miura S, Hibi T. Teratani T, et al. Among authors: shimamura k. Gastroenterology. 2012 Jan;142(1):152-164.e10. doi: 10.1053/j.gastro.2011.09.049. Epub 2011 Oct 10. Gastroenterology. 2012. PMID: 21995947
Free cholesterol accumulation in hepatic stellate cells: mechanism of liver fibrosis aggravation in nonalcoholic steatohepatitis in mice.
Tomita K, Teratani T, Suzuki T, Shimizu M, Sato H, Narimatsu K, Okada Y, Kurihara C, Irie R, Yokoyama H, Shimamura K, Usui S, Ebinuma H, Saito H, Watanabe C, Komoto S, Kawaguchi A, Nagao S, Sugiyama K, Hokari R, Kanai T, Miura S, Hibi T. Tomita K, et al. Among authors: shimamura k. Hepatology. 2014 Jan;59(1):154-69. doi: 10.1002/hep.26604. Epub 2013 Nov 18. Hepatology. 2014. PMID: 23832448
A Hereditary Enteropathy Caused by Mutations in the SLCO2A1 Gene, Encoding a Prostaglandin Transporter.
Umeno J, Hisamatsu T, Esaki M, Hirano A, Kubokura N, Asano K, Kochi S, Yanai S, Fuyuno Y, Shimamura K, Hosoe N, Ogata H, Watanabe T, Aoyagi K, Ooi H, Watanabe K, Yasukawa S, Hirai F, Matsui T, Iida M, Yao T, Hibi T, Kosaki K, Kanai T, Kitazono T, Matsumoto T. Umeno J, et al. Among authors: shimamura k. PLoS Genet. 2015 Nov 5;11(11):e1005581. doi: 10.1371/journal.pgen.1005581. eCollection 2015 Nov. PLoS Genet. 2015. PMID: 26539716 Free PMC article.
710 results