Marschalek R - Search Results

1

From a multipotent stilbene to soluble epoxide hydrolase inhibitors with antiproliferative properties.

Buscató E, Büttner D, Brüggerhoff A, Klingler FM, Weber J, Scholz B, Zivković A, Marschalek R, Stark H, Steinhilber D, Bode HB, Proschak E. Buscató E, et al. Among authors: marschalek r. ChemMedChem. 2013 Jun;8(6):919-23. doi: 10.1002/cmdc.201300057. Epub 2013 Apr 17. ChemMedChem. 2013. PMID: 23596124

2

The leukemogenic AF4-MLL fusion protein causes P-TEFb kinase activation and altered epigenetic signatures.

Benedikt A, Baltruschat S, Scholz B, Bursen A, Arrey TN, Meyer B, Varagnolo L, Müller AM, Karas M, Dingermann T, Marschalek R. Benedikt A, et al. Among authors: marschalek r. Leukemia. 2011 Jan;25(1):135-44. doi: 10.1038/leu.2010.249. Epub 2010 Oct 29. Leukemia. 2011. PMID: 21030982

3

Epigenetics and blood disorders.

Scholz B, Marschalek R. Scholz B, et al. Among authors: marschalek r. Br J Haematol. 2012 Aug;158(3):307-22. doi: 10.1111/j.1365-2141.2012.09193.x. Epub 2012 Jun 20. Br J Haematol. 2012. PMID: 22712628 Free article. Review.

4

Inhibition of class I HDACs abrogates the dominant effect of MLL-AF4 by activation of wild-type MLL.

Ahmad K, Katryniok C, Scholz B, Merkens J, Löscher D, Marschalek R, Steinhilber D. Ahmad K, et al. Among authors: marschalek r. Oncogenesis. 2014 Nov 17;3(11):e127. doi: 10.1038/oncsis.2014.39. Oncogenesis. 2014. PMID: 25402609 Free PMC article.

5

AF4 and AF4N protein complexes: recruitment of P-TEFb kinase, their interactome and potential functions.

Scholz B, Kowarz E, Rössler T, Ahmad K, Steinhilber D, Marschalek R. Scholz B, et al. Among authors: marschalek r. Am J Blood Res. 2015 Jun 15;5(1):10-24. eCollection 2015. Am J Blood Res. 2015. PMID: 26171280 Free PMC article.

6

AF4 and AF4-MLL mediate transcriptional elongation of 5-lipoxygenase mRNA by 1, 25-dihydroxyvitamin D3.

Ahmad K, Scholz B, Capelo R, Schweighöfer I, Kahnt AS, Marschalek R, Steinhilber D. Ahmad K, et al. Among authors: marschalek r. Oncotarget. 2015 Sep 22;6(28):25784-800. doi: 10.18632/oncotarget.4703. Oncotarget. 2015. PMID: 26329759 Free PMC article.

7

Characterization and cellular localization of human 5-lipoxygenase and its protein isoforms 5-LOΔ13, 5-LOΔ4 and 5-LOp12.

Ball AK, Beilstein K, Wittmann S, Sürün D, Saul MJ, Schnütgen F, Flamand N, Capelo R, Kahnt AS, Frey H, Schaefer L, Marschalek R, Häfner AK, Steinhilber D. Ball AK, et al. Among authors: marschalek r. Biochim Biophys Acta Mol Cell Biol Lipids. 2017 May;1862(5):561-571. doi: 10.1016/j.bbalip.2017.02.015. Epub 2017 Feb 28. Biochim Biophys Acta Mol Cell Biol Lipids. 2017. PMID: 28257804

8

TGFβ/SMAD signalling modulates MLL and MLL-AF4 mediated 5-lipoxygenase promoter activation.

Saul MJ, Groher F, Hegewald AB, Müller-McNicoll M, Marschalek R, Suess B, Steinhilber D. Saul MJ, et al. Among authors: marschalek r. Prostaglandins Other Lipid Mediat. 2017 Nov;133:60-67. doi: 10.1016/j.prostaglandins.2017.07.006. Epub 2017 Aug 11. Prostaglandins Other Lipid Mediat. 2017. PMID: 28803964

9

How to effectively treat acute leukemia patients bearing MLL-rearrangements ?

Steinhilber D, Marschalek R. Steinhilber D, et al. Among authors: marschalek r. Biochem Pharmacol. 2018 Jan;147:183-190. doi: 10.1016/j.bcp.2017.09.007. Epub 2017 Sep 21. Biochem Pharmacol. 2018. PMID: 28943239 Free article. Review.

10

Closantel is an allosteric inhibitor of human Taspase1.

Luciano V, Proschak E, Langer JD, Knapp S, Heering J, Marschalek R. Luciano V, et al. Among authors: marschalek r. iScience. 2021 Nov 27;24(12):103524. doi: 10.1016/j.isci.2021.103524. eCollection 2021 Dec 17. iScience. 2021. PMID: 34934933 Free PMC article.

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