Min X - Search Results

1

Molecular basis of sphingosine kinase 1 substrate recognition and catalysis.

Wang Z, Min X, Xiao SH, Johnstone S, Romanow W, Meininger D, Xu H, Liu J, Dai J, An S, Thibault S, Walker N. Wang Z, et al. Among authors: min x. Structure. 2013 May 7;21(5):798-809. doi: 10.1016/j.str.2013.02.025. Epub 2013 Apr 18. Structure. 2013. PMID: 23602659 Free article.

2

Structure guided design of a series of sphingosine kinase (SphK) inhibitors.

Gustin DJ, Li Y, Brown ML, Min X, Schmitt MJ, Wanska M, Wang X, Connors R, Johnstone S, Cardozo M, Cheng AC, Jeffries S, Franks B, Li S, Shen S, Wong M, Wesche H, Xu G, Carlson TJ, Plant M, Morgenstern K, Rex K, Schmitt J, Coxon A, Walker N, Kayser F, Wang Z. Gustin DJ, et al. Among authors: min x. Bioorg Med Chem Lett. 2013 Aug 15;23(16):4608-16. doi: 10.1016/j.bmcl.2013.06.030. Epub 2013 Jun 20. Bioorg Med Chem Lett. 2013. PMID: 23845219

3

Structural and Functional Characterization of the JH2 Pseudokinase Domain of JAK Family Tyrosine Kinase 2 (TYK2).

Min X, Ungureanu D, Maxwell S, Hammarén H, Thibault S, Hillert EK, Ayres M, Greenfield B, Eksterowicz J, Gabel C, Walker N, Silvennoinen O, Wang Z. Min X, et al. J Biol Chem. 2015 Nov 6;290(45):27261-27270. doi: 10.1074/jbc.M115.672048. Epub 2015 Sep 10. J Biol Chem. 2015. PMID: 26359499 Free PMC article.

4

Agonistic β-Klotho antibody mimics fibroblast growth factor 21 (FGF21) functions.

Min X, Weiszmann J, Johnstone S, Wang W, Yu X, Romanow W, Thibault S, Li Y, Wang Z. Min X, et al. J Biol Chem. 2018 Sep 21;293(38):14678-14688. doi: 10.1074/jbc.RA118.004343. Epub 2018 Aug 1. J Biol Chem. 2018. PMID: 30068552 Free PMC article.

5

Discovery and molecular basis of potent noncovalent inhibitors of fatty acid amide hydrolase (FAAH).

Min X, Thibault ST, Porter AC, Gustin DJ, Carlson TJ, Xu H, Lindstrom M, Xu G, Uyeda C, Ma Z, Li Y, Kayser F, Walker NP, Wang Z. Min X, et al. Proc Natl Acad Sci U S A. 2011 May 3;108(18):7379-84. doi: 10.1073/pnas.1016167108. Epub 2011 Apr 18. Proc Natl Acad Sci U S A. 2011. PMID: 21502526 Free PMC article.

6

Crystal structure of a single-chain trimer of human adiponectin globular domain.

Min X, Lemon B, Tang J, Liu Q, Zhang R, Walker N, Li Y, Wang Z. Min X, et al. FEBS Lett. 2012 Mar 23;586(6):912-7. doi: 10.1016/j.febslet.2012.02.024. Epub 2012 Feb 22. FEBS Lett. 2012. PMID: 22449980 Free article.

7

Structure-guided design, synthesis, and evaluation of guanine-derived inhibitors of the eIF4E mRNA-cap interaction.

Chen X, Kopecky DJ, Mihalic J, Jeffries S, Min X, Heath J, Deignan J, Lai S, Fu Z, Guimaraes C, Shen S, Li S, Johnstone S, Thibault S, Xu H, Cardozo M, Shen W, Walker N, Kayser F, Wang Z. Chen X, et al. Among authors: min x. J Med Chem. 2012 Apr 26;55(8):3837-51. doi: 10.1021/jm300037x. Epub 2012 Apr 18. J Med Chem. 2012. PMID: 22458568

8

Structure of the nuclear factor κB-inducing kinase (NIK) kinase domain reveals a constitutively active conformation.

Liu J, Sudom A, Min X, Cao Z, Gao X, Ayres M, Lee F, Cao P, Johnstone S, Plotnikova O, Walker N, Chen G, Wang Z. Liu J, et al. Among authors: min x. J Biol Chem. 2012 Aug 10;287(33):27326-34. doi: 10.1074/jbc.M112.366658. Epub 2012 Jun 20. J Biol Chem. 2012. PMID: 22718757 Free PMC article.

9

Molecular mechanism of an antagonistic antibody against glucose-dependent insulinotropic polypeptide receptor.

Min X, Yie J, Wang J, Chung BC, Huang CS, Xu H, Yang J, Deng L, Lin J, Chen Q, Abbott CM, Gundel C, Thibault SA, Meng T, Bates DL, Lloyd DJ, Véniant MM, Wang Z. Min X, et al. MAbs. 2020 Jan-Dec;12(1):1710047. doi: 10.1080/19420862.2019.1710047. MAbs. 2020. PMID: 31905038 Free PMC article.

10

Structure-guided Discovery of Dual-recognition Chemibodies.

Cheng AC, Doherty EM, Johnstone S, DiMauro EF, Dao J, Luthra A, Ye J, Tang J, Nixey T, Min X, Tagari P, Miranda LP, Wang Z. Cheng AC, et al. Among authors: min x. Sci Rep. 2018 May 15;8(1):7570. doi: 10.1038/s41598-018-25848-0. Sci Rep. 2018. PMID: 29765112 Free PMC article.

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