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Page 1
Dehydrated hereditary stomatocytosis linked to gain-of-function mutations in mechanically activated PIEZO1 ion channels.
Albuisson J, Murthy SE, Bandell M, Coste B, Louis-Dit-Picard H, Mathur J, Fénéant-Thibault M, Tertian G, de Jaureguiberry JP, Syfuss PY, Cahalan S, Garçon L, Toutain F, Simon Rohrlich P, Delaunay J, Picard V, Jeunemaitre X, Patapoutian A. Albuisson J, et al. Among authors: mathur j. Nat Commun. 2013;4:1884. doi: 10.1038/ncomms2899. Nat Commun. 2013. PMID: 23695678 Free PMC article.
Piezo proteins are pore-forming subunits of mechanically activated channels.
Coste B, Xiao B, Santos JS, Syeda R, Grandl J, Spencer KS, Kim SE, Schmidt M, Mathur J, Dubin AE, Montal M, Patapoutian A. Coste B, et al. Among authors: mathur j. Nature. 2012 Feb 19;483(7388):176-81. doi: 10.1038/nature10812. Nature. 2012. PMID: 22343900 Free PMC article.
Gain-of-function mutations in the mechanically activated ion channel PIEZO2 cause a subtype of Distal Arthrogryposis.
Coste B, Houge G, Murray MF, Stitziel N, Bandell M, Giovanni MA, Philippakis A, Hoischen A, Riemer G, Steen U, Steen VM, Mathur J, Cox J, Lebo M, Rehm H, Weiss ST, Wood JN, Maas RL, Sunyaev SR, Patapoutian A. Coste B, et al. Among authors: mathur j. Proc Natl Acad Sci U S A. 2013 Mar 19;110(12):4667-72. doi: 10.1073/pnas.1221400110. Epub 2013 Mar 4. Proc Natl Acad Sci U S A. 2013. PMID: 23487782 Free PMC article.
Piezo1, a mechanically activated ion channel, is required for vascular development in mice.
Ranade SS, Qiu Z, Woo SH, Hur SS, Murthy SE, Cahalan SM, Xu J, Mathur J, Bandell M, Coste B, Li YS, Chien S, Patapoutian A. Ranade SS, et al. Among authors: mathur j. Proc Natl Acad Sci U S A. 2014 Jul 15;111(28):10347-52. doi: 10.1073/pnas.1409233111. Epub 2014 Jun 23. Proc Natl Acad Sci U S A. 2014. PMID: 24958852 Free PMC article.
Piezo2 is the major transducer of mechanical forces for touch sensation in mice.
Ranade SS, Woo SH, Dubin AE, Moshourab RA, Wetzel C, Petrus M, Mathur J, Bégay V, Coste B, Mainquist J, Wilson AJ, Francisco AG, Reddy K, Qiu Z, Wood JN, Lewin GR, Patapoutian A. Ranade SS, et al. Among authors: mathur j. Nature. 2014 Dec 4;516(7529):121-5. doi: 10.1038/nature13980. Nature. 2014. PMID: 25471886 Free PMC article.
Chemical activation of the mechanotransduction channel Piezo1.
Syeda R, Xu J, Dubin AE, Coste B, Mathur J, Huynh T, Matzen J, Lao J, Tully DC, Engels IH, Petrassi HM, Schumacher AM, Montal M, Bandell M, Patapoutian A. Syeda R, et al. Among authors: mathur j. Elife. 2015 May 22;4:e07369. doi: 10.7554/eLife.07369. Elife. 2015. PMID: 26001275 Free PMC article.
267 results