Subramanian V - Search Results

1

Peptidylarginine deiminase inhibition is immunomodulatory and vasculoprotective in murine lupus.

Knight JS, Zhao W, Luo W, Subramanian V, O'Dell AA, Yalavarthi S, Hodgin JB, Eitzman DT, Thompson PR, Kaplan MJ. Knight JS, et al. Among authors: subramanian v. J Clin Invest. 2013 Jul;123(7):2981-93. doi: 10.1172/JCI67390. Epub 2013 Jun 3. J Clin Invest. 2013. PMID: 23722903 Free PMC article.

2

Peptidylarginine deiminase inhibition reduces vascular damage and modulates innate immune responses in murine models of atherosclerosis.

Knight JS, Luo W, O'Dell AA, Yalavarthi S, Zhao W, Subramanian V, Guo C, Grenn RC, Thompson PR, Eitzman DT, Kaplan MJ. Knight JS, et al. Among authors: subramanian v. Circ Res. 2014 Mar 14;114(6):947-56. doi: 10.1161/CIRCRESAHA.114.303312. Epub 2014 Jan 14. Circ Res. 2014. PMID: 24425713 Free PMC article.

3

Peptidylarginine deiminase inhibition disrupts NET formation and protects against kidney, skin and vascular disease in lupus-prone MRL/lpr mice.

Knight JS, Subramanian V, O'Dell AA, Yalavarthi S, Zhao W, Smith CK, Hodgin JB, Thompson PR, Kaplan MJ. Knight JS, et al. Among authors: subramanian v. Ann Rheum Dis. 2015 Dec;74(12):2199-206. doi: 10.1136/annrheumdis-2014-205365. Epub 2014 Aug 7. Ann Rheum Dis. 2015. PMID: 25104775 Free PMC article.

4

Neutrophil extracellular trap-derived enzymes oxidize high-density lipoprotein: an additional proatherogenic mechanism in systemic lupus erythematosus.

Smith CK, Vivekanandan-Giri A, Tang C, Knight JS, Mathew A, Padilla RL, Gillespie BW, Carmona-Rivera C, Liu X, Subramanian V, Hasni S, Thompson PR, Heinecke JW, Saran R, Pennathur S, Kaplan MJ. Smith CK, et al. Among authors: subramanian v. Arthritis Rheumatol. 2014 Sep;66(9):2532-2544. doi: 10.1002/art.38703. Arthritis Rheumatol. 2014. PMID: 24838349 Free PMC article.

5

NETs are a source of citrullinated autoantigens and stimulate inflammatory responses in rheumatoid arthritis.

Khandpur R, Carmona-Rivera C, Vivekanandan-Giri A, Gizinski A, Yalavarthi S, Knight JS, Friday S, Li S, Patel RM, Subramanian V, Thompson P, Chen P, Fox DA, Pennathur S, Kaplan MJ. Khandpur R, et al. Among authors: subramanian v. Sci Transl Med. 2013 Mar 27;5(178):178ra40. doi: 10.1126/scitranslmed.3005580. Sci Transl Med. 2013. PMID: 23536012 Free PMC article.

6

Design, synthesis, and biological evaluation of tetrazole analogs of Cl-amidine as protein arginine deiminase inhibitors.

Subramanian V, Knight JS, Parelkar S, Anguish L, Coonrod SA, Kaplan MJ, Thompson PR. Subramanian V, et al. J Med Chem. 2015 Feb 12;58(3):1337-44. doi: 10.1021/jm501636x. Epub 2015 Jan 16. J Med Chem. 2015. PMID: 25559347 Free PMC article.

7

Abrogation of collagen-induced arthritis by a peptidyl arginine deiminase inhibitor is associated with modulation of T cell-mediated immune responses.

Kawalkowska J, Quirke AM, Ghari F, Davis S, Subramanian V, Thompson PR, Williams RO, Fischer R, La Thangue NB, Venables PJ. Kawalkowska J, et al. Among authors: subramanian v. Sci Rep. 2016 May 23;6:26430. doi: 10.1038/srep26430. Sci Rep. 2016. PMID: 27210478 Free PMC article.

8

Modulation of calcium-induced cell death in human neural stem cells by the novel peptidylarginine deiminase-AIF pathway.

U KP, Subramanian V, Nicholas AP, Thompson PR, Ferretti P. U KP, et al. Among authors: subramanian v. Biochim Biophys Acta. 2014 Jun;1843(6):1162-71. doi: 10.1016/j.bbamcr.2014.02.018. Epub 2014 Mar 5. Biochim Biophys Acta. 2014. PMID: 24607566 Free PMC article.

9

Peptidylarginine deiminases: novel drug targets for prevention of neuronal damage following hypoxic ischemic insult (HI) in neonates.

Lange S, Rocha-Ferreira E, Thei L, Mawjee P, Bennett K, Thompson PR, Subramanian V, Nicholas AP, Peebles D, Hristova M, Raivich G. Lange S, et al. Among authors: subramanian v. J Neurochem. 2014 Aug;130(4):555-62. doi: 10.1111/jnc.12744. Epub 2014 May 24. J Neurochem. 2014. PMID: 24762056 Free PMC article.

10

Inhibiting protein arginine deiminases has antioxidant consequences.

Witalison EE, Cui X, Hofseth AB, Subramanian V, Causey CP, Thompson PR, Hofseth LJ. Witalison EE, et al. Among authors: subramanian v. J Pharmacol Exp Ther. 2015 Apr;353(1):64-70. doi: 10.1124/jpet.115.222745. Epub 2015 Jan 29. J Pharmacol Exp Ther. 2015. PMID: 25635139 Free PMC article.

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