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Gamma rays induce a p53-independent mitochondrial biogenesis that is counter-regulated by HIF1α.
Bartoletti-Stella A, Mariani E, Kurelac I, Maresca A, Caratozzolo MF, Iommarini L, Carelli V, Eusebi LH, Guido A, Cenacchi G, Fuccio L, Rugolo M, Tullo A, Porcelli AM, Gasparre G. Bartoletti-Stella A, et al. Among authors: kurelac i. Cell Death Dis. 2013 Jun 13;4(6):e663. doi: 10.1038/cddis.2013.187. Cell Death Dis. 2013. PMID: 23764844 Free PMC article.
Mitochondrial metabolism and cancer.
Kurelac I, Romeo G, Gasparre G. Kurelac I, et al. Mitochondrion. 2011 Jul;11(4):635-7. doi: 10.1016/j.mito.2011.03.012. Epub 2011 Apr 5. Mitochondrion. 2011. PMID: 21447406 No abstract available.
A mutation threshold distinguishes the antitumorigenic effects of the mitochondrial gene MTND1, an oncojanus function.
Gasparre G, Kurelac I, Capristo M, Iommarini L, Ghelli A, Ceccarelli C, Nicoletti G, Nanni P, De Giovanni C, Scotlandi K, Betts CM, Carelli V, Lollini PL, Romeo G, Rugolo M, Porcelli AM. Gasparre G, et al. Among authors: kurelac i. Cancer Res. 2011 Oct 1;71(19):6220-9. doi: 10.1158/0008-5472.CAN-11-1042. Epub 2011 Aug 18. Cancer Res. 2011. PMID: 21852384
Somatic complex I disruptive mitochondrial DNA mutations are modifiers of tumorigenesis that correlate with low genomic instability in pituitary adenomas.
Kurelac I, MacKay A, Lambros MB, Di Cesare E, Cenacchi G, Ceccarelli C, Morra I, Melcarne A, Morandi L, Calabrese FM, Attimonelli M, Tallini G, Reis-Filho JS, Gasparre G. Kurelac I, et al. Hum Mol Genet. 2013 Jan 15;22(2):226-38. doi: 10.1093/hmg/dds422. Epub 2012 Oct 9. Hum Mol Genet. 2013. PMID: 23049073
69 results