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Alendronate treatment of the brtl osteogenesis imperfecta mouse improves femoral geometry and load response before fracture but decreases predicted material properties and has detrimental effects on osteoblasts and bone formation.
Uveges TE, Kozloff KM, Ty JM, Ledgard F, Raggio CL, Gronowicz G, Goldstein SA, Marini JC. Uveges TE, et al. Among authors: marini jc. J Bone Miner Res. 2009 May;24(5):849-59. doi: 10.1359/jbmr.081238. J Bone Miner Res. 2009. PMID: 19113917 Free PMC article.
In utero transplantation of adult bone marrow decreases perinatal lethality and rescues the bone phenotype in the knockin murine model for classical, dominant osteogenesis imperfecta.
Panaroni C, Gioia R, Lupi A, Besio R, Goldstein SA, Kreider J, Leikin S, Vera JC, Mertz EL, Perilli E, Baruffaldi F, Villa I, Farina A, Casasco M, Cetta G, Rossi A, Frattini A, Marini JC, Vezzoni P, Forlino A. Panaroni C, et al. Among authors: marini jc. Blood. 2009 Jul 9;114(2):459-68. doi: 10.1182/blood-2008-12-195859. Epub 2009 May 4. Blood. 2009. PMID: 19414862 Free PMC article.
253 results