DeFranco A - Search Results

1

Cutting edge: ABIN-1 protects against psoriasis by restricting MyD88 signals in dendritic cells.

Callahan JA, Hammer GE, Agelides A, Duong BH, Oshima S, North J, Advincula R, Shifrin N, Truong HA, Paw J, Barrera J, DeFranco A, Rosenblum MD, Malynn BA, Ma A. Callahan JA, et al. Among authors: defranco a. J Immunol. 2013 Jul 15;191(2):535-9. doi: 10.4049/jimmunol.1203335. Epub 2013 Jun 19. J Immunol. 2013. PMID: 23785118 Free PMC article.

2

Expression of A20 by dendritic cells preserves immune homeostasis and prevents colitis and spondyloarthritis.

Hammer GE, Turer EE, Taylor KE, Fang CJ, Advincula R, Oshima S, Barrera J, Huang EJ, Hou B, Malynn BA, Reizis B, DeFranco A, Criswell LA, Nakamura MC, Ma A. Hammer GE, et al. Among authors: defranco a. Nat Immunol. 2011 Oct 23;12(12):1184-93. doi: 10.1038/ni.2135. Nat Immunol. 2011. PMID: 22019834 Free PMC article.

3

B cell-specific loss of Lyn kinase leads to autoimmunity.

Lamagna C, Hu Y, DeFranco AL, Lowell CA. Lamagna C, et al. Among authors: defranco al. J Immunol. 2014 Feb 1;192(3):919-28. doi: 10.4049/jimmunol.1301979. Epub 2013 Dec 27. J Immunol. 2014. PMID: 24376269 Free PMC article.

4

B Cell-Intrinsic MyD88 Signaling Promotes Initial Cell Proliferation and Differentiation To Enhance the Germinal Center Response to a Virus-like Particle.

Tian M, Hua Z, Hong S, Zhang Z, Liu C, Lin L, Chen J, Zhang W, Zhou X, Zhang F, DeFranco AL, Hou B. Tian M, et al. J Immunol. 2018 Feb 1;200(3):937-948. doi: 10.4049/jimmunol.1701067. Epub 2017 Dec 27. J Immunol. 2018. PMID: 29282308

5

Prolonged production of reactive oxygen species in response to B cell receptor stimulation promotes B cell activation and proliferation.

Wheeler ML, Defranco AL. Wheeler ML, et al. J Immunol. 2012 Nov 1;189(9):4405-16. doi: 10.4049/jimmunol.1201433. Epub 2012 Sep 28. J Immunol. 2012. PMID: 23024271 Free PMC article.

6

Hyperactivated MyD88 signaling in dendritic cells, through specific deletion of Lyn kinase, causes severe autoimmunity and inflammation.

Lamagna C, Scapini P, van Ziffle JA, DeFranco AL, Lowell CA. Lamagna C, et al. Among authors: defranco al. Proc Natl Acad Sci U S A. 2013 Aug 27;110(35):E3311-20. doi: 10.1073/pnas.1300617110. Epub 2013 Aug 12. Proc Natl Acad Sci U S A. 2013. PMID: 23940344 Free PMC article.

7

Normal development and activation but altered cytokine production of Fyn-deficient CD4+ T cells.

Mamchak AA, Sullivan BM, Hou B, Lee LM, Gilden JK, Krummel MF, Locksley RM, DeFranco AL. Mamchak AA, et al. Among authors: defranco al. J Immunol. 2008 Oct 15;181(8):5374-85. doi: 10.4049/jimmunol.181.8.5374. J Immunol. 2008. PMID: 18832694 Free PMC article.

8

Developmental acquisition of the Lyn-CD22-SHP-1 inhibitory pathway promotes B cell tolerance.

Gross AJ, Lyandres JR, Panigrahi AK, Prak ET, DeFranco AL. Gross AJ, et al. J Immunol. 2009 May 1;182(9):5382-92. doi: 10.4049/jimmunol.0803941. J Immunol. 2009. PMID: 19380785 Free PMC article.

9

Role of MyD88 signaling in the imiquimod-induced mouse model of psoriasis: focus on innate myeloid cells.

Costa S, Marini O, Bevilacqua D, DeFranco AL, Hou B, Lonardi S, Vermi W, Rodegher P, Panato A, Tagliaro F, Lowell CA, Cassatella MA, Girolomoni G, Scapini P. Costa S, et al. Among authors: defranco al. J Leukoc Biol. 2017 Sep;102(3):791-803. doi: 10.1189/jlb.3MA0217-054RR. Epub 2017 Jun 22. J Leukoc Biol. 2017. PMID: 28642279 Free PMC article.

10

Requirement for MyD88 signaling in B cells and dendritic cells for germinal center anti-nuclear antibody production in Lyn-deficient mice.

Hua Z, Gross AJ, Lamagna C, Ramos-Hernández N, Scapini P, Ji M, Shao H, Lowell CA, Hou B, DeFranco AL. Hua Z, et al. Among authors: defranco al. J Immunol. 2014 Feb 1;192(3):875-85. doi: 10.4049/jimmunol.1300683. Epub 2013 Dec 30. J Immunol. 2014. PMID: 24379120 Free PMC article.

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