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The ubiquitin-modifying enzyme A20 restricts ubiquitination of the kinase RIPK3 and protects cells from necroptosis.
Onizawa M, Oshima S, Schulze-Topphoff U, Oses-Prieto JA, Lu T, Tavares R, Prodhomme T, Duong B, Whang MI, Advincula R, Agelidis A, Barrera J, Wu H, Burlingame A, Malynn BA, Zamvil SS, Ma A. Onizawa M, et al. Among authors: malynn ba. Nat Immunol. 2015 Jun;16(6):618-27. doi: 10.1038/ni.3172. Epub 2015 May 4. Nat Immunol. 2015. PMID: 25939025 Free PMC article.
A20 and ABIN-1 synergistically preserve intestinal epithelial cell survival.
Kattah MG, Shao L, Rosli YY, Shimizu H, Whang MI, Advincula R, Achacoso P, Shah S, Duong BH, Onizawa M, Tanbun P, Malynn BA, Ma A. Kattah MG, et al. Among authors: malynn ba. J Exp Med. 2018 Jul 2;215(7):1839-1852. doi: 10.1084/jem.20180198. Epub 2018 Jun 21. J Exp Med. 2018. PMID: 29930103 Free PMC article.
Hypomorphic A20 expression confers susceptibility to psoriasis.
Aki A, Nagasaki M, Malynn BA, Ma A, Kagari T. Aki A, et al. Among authors: malynn ba. PLoS One. 2017 Jun 28;12(6):e0180481. doi: 10.1371/journal.pone.0180481. eCollection 2017. PLoS One. 2017. PMID: 28658319 Free PMC article.
48 results