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Page 1
TRF2 inhibits a cell-extrinsic pathway through which natural killer cells eliminate cancer cells.
Biroccio A, Cherfils-Vicini J, Augereau A, Pinte S, Bauwens S, Ye J, Simonet T, Horard B, Jamet K, Cervera L, Mendez-Bermudez A, Poncet D, Grataroli R, de Rodenbeeke CT, Salvati E, Rizzo A, Zizza P, Ricoul M, Cognet C, Kuilman T, Duret H, Lépinasse F, Marvel J, Verhoeyen E, Cosset FL, Peeper D, Smyth MJ, Londoño-Vallejo A, Sabatier L, Picco V, Pages G, Scoazec JY, Stoppacciaro A, Leonetti C, Vivier E, Gilson E. Biroccio A, et al. Among authors: zizza p. Nat Cell Biol. 2013 Jul;15(7):818-28. doi: 10.1038/ncb2774. Epub 2013 Jun 23. Nat Cell Biol. 2013. PMID: 23792691
On and off-target effects of telomere uncapping G-quadruplex selective ligands based on pentacyclic acridinium salts.
Iachettini S, Stevens MF, Frigerio M, Hummersone MG, Hutchinson I, Garner TP, Searle MS, Wilson DW, Munde M, Nanjunda R, D'Angelo C, Zizza P, Rizzo A, Cingolani C, De Cicco F, Porru M, D'Incalci M, Leonetti C, Biroccio A, Salvati E. Iachettini S, et al. Among authors: zizza p. J Exp Clin Cancer Res. 2013 Sep 19;32(1):68. doi: 10.1186/1756-9966-32-68. J Exp Clin Cancer Res. 2013. PMID: 24330541 Free PMC article.
Evidence for G-quadruplex in the promoter of vegfr-2 and its targeting to inhibit tumor angiogenesis.
Salvati E, Zizza P, Rizzo A, Iachettini S, Cingolani C, D'Angelo C, Porru M, Randazzo A, Pagano B, Novellino E, Pisanu ME, Stoppacciaro A, Spinella F, Bagnato A, Gilson E, Leonetti C, Biroccio A. Salvati E, et al. Among authors: zizza p. Nucleic Acids Res. 2014 Mar;42(5):2945-57. doi: 10.1093/nar/gkt1289. Epub 2013 Dec 11. Nucleic Acids Res. 2014. PMID: 24335081 Free PMC article.
Shading the TRF2 recruiting function: a new horizon in drug development.
Di Maro S, Zizza P, Salvati E, De Luca V, Capasso C, Fotticchia I, Pagano B, Marinelli L, Gilson E, Novellino E, Cosconati S, Biroccio A. Di Maro S, et al. Among authors: zizza p. J Am Chem Soc. 2014 Dec 3;136(48):16708-11. doi: 10.1021/ja5080773. Epub 2014 Nov 19. J Am Chem Soc. 2014. PMID: 25393214
A basal level of DNA damage and telomere deprotection increases the sensitivity of cancer cells to G-quadruplex interactive compounds.
Salvati E, Rizzo A, Iachettini S, Zizza P, Cingolani C, D'Angelo C, Porru M, Mondello C, Aiello A, Farsetti A, Gilson E, Leonetti C, Biroccio A. Salvati E, et al. Among authors: zizza p. Nucleic Acids Res. 2015 Feb 18;43(3):1759-69. doi: 10.1093/nar/gkv006. Epub 2015 Jan 23. Nucleic Acids Res. 2015. PMID: 25618850 Free PMC article.
EMICORON: A multi-targeting G4 ligand with a promising preclinical profile.
Porru M, Zizza P, Franceschin M, Leonetti C, Biroccio A. Porru M, et al. Among authors: zizza p. Biochim Biophys Acta Gen Subj. 2017 May;1861(5 Pt B):1362-1370. doi: 10.1016/j.bbagen.2016.11.010. Epub 2016 Nov 9. Biochim Biophys Acta Gen Subj. 2017. PMID: 27838395 Review.
46 results