Guarente L - Search Results

1

The NAD(+)/Sirtuin Pathway Modulates Longevity through Activation of Mitochondrial UPR and FOXO Signaling.

Mouchiroud L, Houtkooper RH, Moullan N, Katsyuba E, Ryu D, Cantó C, Mottis A, Jo YS, Viswanathan M, Schoonjans K, Guarente L, Auwerx J. Mouchiroud L, et al. Among authors: guarente l. Cell. 2013 Jul 18;154(2):430-41. doi: 10.1016/j.cell.2013.06.016. Cell. 2013. PMID: 23870130 Free PMC article.

2

A role for SIR-2.1 regulation of ER stress response genes in determining C. elegans life span.

Viswanathan M, Kim SK, Berdichevsky A, Guarente L. Viswanathan M, et al. Among authors: guarente l. Dev Cell. 2005 Nov;9(5):605-15. doi: 10.1016/j.devcel.2005.09.017. Dev Cell. 2005. PMID: 16256736 Free article.

3

C. elegans SIR-2.1 interacts with 14-3-3 proteins to activate DAF-16 and extend life span.

Berdichevsky A, Viswanathan M, Horvitz HR, Guarente L. Berdichevsky A, et al. Among authors: guarente l. Cell. 2006 Jun 16;125(6):1165-77. doi: 10.1016/j.cell.2006.04.036. Cell. 2006. PMID: 16777605 Free article.

4

Regulation of Caenorhabditis elegans lifespan by sir-2.1 transgenes.

Viswanathan M, Guarente L. Viswanathan M, et al. Among authors: guarente l. Nature. 2011 Sep 21;477(7365):E1-2. doi: 10.1038/nature10440. Nature. 2011. PMID: 21938026 No abstract available.

5

NAD+ and sirtuins in aging and disease.

Imai S, Guarente L. Imai S, et al. Among authors: guarente l. Trends Cell Biol. 2014 Aug;24(8):464-71. doi: 10.1016/j.tcb.2014.04.002. Epub 2014 Apr 29. Trends Cell Biol. 2014. PMID: 24786309 Free PMC article. Review.

6

SnapShot: sirtuins, NAD, and aging.

Nakagawa T, Guarente L. Nakagawa T, et al. Among authors: guarente l. Cell Metab. 2014 Jul 1;20(1):192-192.e1. doi: 10.1016/j.cmet.2014.06.001. Cell Metab. 2014. PMID: 24988458 Free article.

7

Linking DNA damage, NAD(+)/SIRT1, and aging.

Guarente L. Guarente L. Cell Metab. 2014 Nov 4;20(5):706-707. doi: 10.1016/j.cmet.2014.10.015. Epub 2014 Nov 4. Cell Metab. 2014. PMID: 25440052 Free article.

8

Sirtuin deacetylases in neurodegenerative diseases of aging.

Herskovits AZ, Guarente L. Herskovits AZ, et al. Among authors: guarente l. Cell Res. 2013 Jun;23(6):746-58. doi: 10.1038/cr.2013.70. Epub 2013 May 21. Cell Res. 2013. PMID: 23689277 Free PMC article. Review.

9

A stress response pathway involving sirtuins, forkheads and 14-3-3 proteins.

Berdichevsky A, Guarente L. Berdichevsky A, et al. Among authors: guarente l. Cell Cycle. 2006 Nov;5(22):2588-91. doi: 10.4161/cc.5.22.3513. Epub 2006 Nov 15. Cell Cycle. 2006. PMID: 17172829 Review.

10

The NAD+-dependent deacetylase SIRT1 modulates CLOCK-mediated chromatin remodeling and circadian control.

Nakahata Y, Kaluzova M, Grimaldi B, Sahar S, Hirayama J, Chen D, Guarente LP, Sassone-Corsi P. Nakahata Y, et al. Cell. 2008 Jul 25;134(2):329-40. doi: 10.1016/j.cell.2008.07.002. Cell. 2008. PMID: 18662547 Free PMC article.

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