Caddick S - Search Results

1

Acid-cleavable thiomaleamic acid linker for homogeneous antibody-drug conjugation.

Castañeda L, Maruani A, Schumacher FF, Miranda E, Chudasama V, Chester KA, Baker JR, Smith ME, Caddick S. Castañeda L, et al. Among authors: caddick s. Chem Commun (Camb). 2013 Sep 25;49(74):8187-9. doi: 10.1039/c3cc45220d. Chem Commun (Camb). 2013. PMID: 23929130 Free PMC article.

2

Tunable reagents for multi-functional bioconjugation: reversible or permanent chemical modification of proteins and peptides by control of maleimide hydrolysis.

Ryan CP, Smith ME, Schumacher FF, Grohmann D, Papaioannou D, Waksman G, Werner F, Baker JR, Caddick S. Ryan CP, et al. Among authors: caddick s. Chem Commun (Camb). 2011 May 21;47(19):5452-4. doi: 10.1039/c1cc11114k. Epub 2011 Apr 5. Chem Commun (Camb). 2011. PMID: 21465057 Free PMC article.

3

Bromopyridazinedione-mediated protein and peptide bioconjugation.

Chudasama V, Smith ME, Schumacher FF, Papaioannou D, Waksman G, Baker JR, Caddick S. Chudasama V, et al. Among authors: caddick s. Chem Commun (Camb). 2011 Aug 21;47(31):8781-3. doi: 10.1039/c1cc12807h. Epub 2011 Jul 7. Chem Commun (Camb). 2011. PMID: 21738916 Free PMC article.

4

Homogeneous antibody fragment conjugation by disulfide bridging introduces 'spinostics'.

Schumacher FF, Sanchania VA, Tolner B, Wright ZV, Ryan CP, Smith ME, Ward JM, Caddick S, Kay CW, Aeppli G, Chester KA, Baker JR. Schumacher FF, et al. Among authors: caddick s. Sci Rep. 2013;3:1525. doi: 10.1038/srep01525. Sci Rep. 2013. PMID: 23519366 Free PMC article.

5

Next generation maleimides enable the controlled assembly of antibody-drug conjugates via native disulfide bond bridging.

Schumacher FF, Nunes JP, Maruani A, Chudasama V, Smith ME, Chester KA, Baker JR, Caddick S. Schumacher FF, et al. Among authors: caddick s. Org Biomol Chem. 2014 Oct 7;12(37):7261-9. doi: 10.1039/c4ob01550a. Org Biomol Chem. 2014. PMID: 25103319 Free PMC article.

6

Functional native disulfide bridging enables delivery of a potent, stable and targeted antibody-drug conjugate (ADC).

Nunes JP, Morais M, Vassileva V, Robinson E, Rajkumar VS, Smith ME, Pedley RB, Caddick S, Baker JR, Chudasama V. Nunes JP, et al. Among authors: caddick s. Chem Commun (Camb). 2015 Jul 7;51(53):10624-7. doi: 10.1039/c5cc03557k. Epub 2015 Jun 5. Chem Commun (Camb). 2015. PMID: 26051118 Free article.

7

Site-selective multi-porphyrin attachment enables the formation of a next-generation antibody-based photodynamic therapeutic.

Maruani A, Savoie H, Bryden F, Caddick S, Boyle R, Chudasama V. Maruani A, et al. Among authors: caddick s. Chem Commun (Camb). 2015 Oct 25;51(83):15304-7. doi: 10.1039/c5cc06985h. Epub 2015 Sep 4. Chem Commun (Camb). 2015. PMID: 26340593

8

Recent advances in the construction of antibody-drug conjugates.

Chudasama V, Maruani A, Caddick S. Chudasama V, et al. Among authors: caddick s. Nat Chem. 2016 Feb;8(2):114-9. doi: 10.1038/nchem.2415. Epub 2016 Jan 4. Nat Chem. 2016. PMID: 26791893

9

A rapid, site-selective and efficient route to the dual modification of DARPins.

Moody P, Chudasama V, Nathani RI, Maruani A, Martin S, Smith ME, Caddick S. Moody P, et al. Among authors: caddick s. Chem Commun (Camb). 2014 May 18;50(38):4898-900. doi: 10.1039/c4cc00053f. Chem Commun (Camb). 2014. PMID: 24687090 Free PMC article.

10

Dioxygen mediated hydroacylation of vinyl sulfonates and sulfones on water.

Chudasama V, Fitzmaurice RJ, Ahern JM, Caddick S. Chudasama V, et al. Among authors: caddick s. Chem Commun (Camb). 2010 Jan 7;46(1):133-5. doi: 10.1039/b914563j. Epub 2009 Nov 13. Chem Commun (Camb). 2010. PMID: 20024317

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