Ye JM - Search Results

1

Rutaecarpine analogues reduce lipid accumulation in adipocytes via inhibiting adipogenesis/lipogenesis with AMPK activation and UPR suppression.

Chen YC, Zeng XY, He Y, Liu H, Wang B, Zhou H, Chen JW, Liu PQ, Gu LQ, Ye JM, Huang ZS. Chen YC, et al. Among authors: ye jm. ACS Chem Biol. 2013 Oct 18;8(10):2301-11. doi: 10.1021/cb4003893. Epub 2013 Sep 6. ACS Chem Biol. 2013. PMID: 23962138

2

Rutaecarpine analogues reduce lipid accumulation in adipocytes via inhibiting adipogenesis/lipogenesis with AMPK activation and UPR suppression.

Chen YC, Zeng XY, He Y, Liu H, Wang B, Zhou H, Chen JW, Liu PQ, Gu LQ, Ye JM, Huang ZS. Chen YC, et al. Among authors: ye jm. ACS Chem Biol. 2015 Jun 19;10(6):1570-1. doi: 10.1021/acschembio.5b00242. Epub 2015 Apr 23. ACS Chem Biol. 2015. PMID: 25905901 No abstract available.

3

Discovery of natural alkaloid bouchardatine as a novel inhibitor of adipogenesis/lipogenesis in 3T3-L1 adipocytes.

Rao Y, Liu H, Gao L, Yu H, Tan JH, Ou TM, Huang SL, Gu LQ, Ye JM, Huang ZS. Rao Y, et al. Among authors: ye jm. Bioorg Med Chem. 2015 Aug 1;23(15):4719-4727. doi: 10.1016/j.bmc.2015.05.057. Epub 2015 Jun 5. Bioorg Med Chem. 2015. PMID: 26088335

4

Synthesis and Biological Evaluation of Novel Bouchardatine Derivatives as Potential Adipogenesis/Lipogenesis Inhibitors for Antiobesity Treatment.

Rao Y, Liu H, Gao L, Yu H, Ou TM, Tan JH, Huang SL, Wang HG, Li D, Gu LQ, Ye JM, Huang ZS. Rao Y, et al. Among authors: ye jm. J Med Chem. 2015 Dec 10;58(23):9395-413. doi: 10.1021/acs.jmedchem.5b01566. Epub 2015 Dec 1. J Med Chem. 2015. PMID: 26572282

5

Natural alkaloid bouchardatine ameliorates metabolic disorders in high-fat diet-fed mice by stimulating the sirtuin 1/liver kinase B-1/AMPK axis.

Rao Y, Yu H, Gao L, Lu YT, Xu Z, Liu H, Gu LQ, Ye JM, Huang ZS. Rao Y, et al. Among authors: ye jm. Br J Pharmacol. 2017 Aug;174(15):2457-2470. doi: 10.1111/bph.13855. Epub 2017 Jun 21. Br J Pharmacol. 2017. PMID: 28493443 Free PMC article.

6

Bouchardatine analogue alleviates non-alcoholic hepatic fatty liver disease/non-alcoholic steatohepatitis in high-fat fed mice by inhibiting ATP synthase activity.

Rao Y, Lu YT, Li C, Song QQ, Xu YH, Xu Z, Hu YT, Yu H, Gao L, Gu LQ, Ye JM, Huang ZS. Rao Y, et al. Among authors: ye jm. Br J Pharmacol. 2019 Aug;176(16):2877-2893. doi: 10.1111/bph.14713. Epub 2019 Jul 4. Br J Pharmacol. 2019. PMID: 31113010 Free PMC article.

7

Design, synthesis and biological evaluation of novel bouchardatine analogs as potential inhibitors of adipogenesis/lipogenesis in 3T3-L1 adipocytes.

Gao L, Xu Z, Rao Y, Lu YT, Hu YT, Yu H, Xu YH, Song QQ, Ye JM, Huang ZS. Gao L, et al. Among authors: ye jm. Eur J Med Chem. 2018 Mar 10;147:90-101. doi: 10.1016/j.ejmech.2018.01.089. Epub 2018 Jan 31. Eur J Med Chem. 2018. PMID: 29425817

8

Bouchardatine suppresses rectal cancer in mice by disrupting its metabolic pathways via activating the SIRT1-PGC-1α-UCP2 axis.

Xu YH, Song QQ, Li C, Hu YT, Song BB, Ye JM, Rao Y, Huang ZS. Xu YH, et al. Among authors: ye jm. Eur J Pharmacol. 2019 Jul 5;854:328-337. doi: 10.1016/j.ejphar.2019.04.029. Epub 2019 Apr 24. Eur J Pharmacol. 2019. PMID: 31028741

9

Discovery of a promising agent IQZ23 for the treatment of obesity and related metabolic disorders.

Rao Y, Xu Z, Hu YT, Li C, Xu YH, Song QQ, Yu H, Song BB, Chen SB, Li QJ, Huang SL, Tan JH, Ou TM, Wang HG, Zhong GP, Ye JM, Huang ZS. Rao Y, et al. Among authors: ye jm. Eur J Med Chem. 2020 Apr 15;192:112172. doi: 10.1016/j.ejmech.2020.112172. Epub 2020 Feb 27. Eur J Med Chem. 2020. PMID: 32163815

10

Matrine counteracts obesity in mice via inducing adipose thermogenesis by activating HSF1/PGC-1α axis.

Li C, Xu YH, Hu YT, Zhou X, Huang ZS, Ye JM, Rao Y. Li C, et al. Among authors: ye jm. Pharmacol Res. 2022 Mar;177:106136. doi: 10.1016/j.phrs.2022.106136. Epub 2022 Feb 22. Pharmacol Res. 2022. PMID: 35202821

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