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TGF-β superfamily member Nodal stimulates human β-cell proliferation while maintaining cellular viability.
Endocrinology. 2013 Nov;154(11):4099-112. doi: 10.1210/en.2013-1197. Epub 2013 Aug 22.
Endocrinology. 2013.
PMID: 23970788
Free PMC article.
Perturbation of the Bcl-2 network and an induced Noxa/Bcl-xL interaction trigger mitochondrial dysfunction after DNA damage.
Lopez H, Zhang L, George NM, Liu X, Pang X, Evans JJD, Targy NM, Luo X.
Lopez H, et al. Among authors: targy nm.
J Biol Chem. 2010 May 14;285(20):15016-15026. doi: 10.1074/jbc.M109.086231. Epub 2010 Mar 11.
J Biol Chem. 2010.
PMID: 20223826
Free PMC article.
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Bax contains two functional mitochondrial targeting sequences and translocates to mitochondria in a conformational change- and homo-oligomerization-driven process.
George NM, Targy N, Evans JJ, Zhang L, Luo X.
George NM, et al. Among authors: targy n.
J Biol Chem. 2010 Jan 8;285(2):1384-92. doi: 10.1074/jbc.M109.049924. Epub 2009 Oct 30.
J Biol Chem. 2010.
PMID: 19880508
Free PMC article.
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Active Bax and Bak are functional holins.
Pang X, Moussa SH, Targy NM, Bose JL, George NM, Gries C, Lopez H, Zhang L, Bayles KW, Young R, Luo X.
Pang X, et al. Among authors: targy nm.
Genes Dev. 2011 Nov 1;25(21):2278-90. doi: 10.1101/gad.171645.111. Epub 2011 Oct 17.
Genes Dev. 2011.
PMID: 22006182
Free PMC article.
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