Waddington SN - Search Results

1

Transduction of fetal mice with a feline lentiviral vector induces liver tumors which exhibit an E2F activation signature.

Condiotti R, Goldenberg D, Giladi H, Schnitzer-Perlman T, Waddington SN, Buckley SM, Heim D, Cheung W, Themis M, Coutelle C, Simerzin A, Osejindu E, Wege H, Themis M, Galun E. Condiotti R, et al. Among authors: waddington sn. Mol Ther. 2014 Jan;22(1):59-68. doi: 10.1038/mt.2013.193. Epub 2013 Aug 28. Mol Ther. 2014. PMID: 23982166 Free PMC article.

2

Sustained delivery of therapeutic concentrations of human clotting factor IX--a comparison of adenoviral and AAV vectors administered in utero.

Schneider H, Mühle C, Douar AM, Waddington S, Jiang QJ, von der Mark K, Coutelle C, Rascher W. Schneider H, et al. J Gene Med. 2002 Jan-Feb;4(1):46-53. doi: 10.1002/jgm.233. J Gene Med. 2002. PMID: 11828387

3

In utero gene transfer of human factor IX to fetal mice can induce postnatal tolerance of the exogenous clotting factor.

Waddington SN, Buckley SM, Nivsarkar M, Jezzard S, Schneider H, Dahse T, Kemball-Cook G, Miah M, Tucker N, Dallman MJ, Themis M, Coutelle C. Waddington SN, et al. Blood. 2003 Feb 15;101(4):1359-66. doi: 10.1182/blood-2002-03-0779. Epub 2002 Oct 3. Blood. 2003. PMID: 12393743 Free article.

4

Ultrasound-guided percutaneous delivery of adenoviral vectors encoding the beta-galactosidase and human factor IX genes to early gestation fetal sheep in utero.

David A, Cook T, Waddington S, Peebles D, Nivsarkar M, Knapton H, Miah M, Dahse T, Noakes D, Schneider H, Rodeck C, Coutelle C, Themis M. David A, et al. Hum Gene Ther. 2003 Mar 1;14(4):353-64. doi: 10.1089/104303403321208952. Hum Gene Ther. 2003. PMID: 12659676

5

Long-term transgene expression by administration of a lentivirus-based vector to the fetal circulation of immuno-competent mice.

Waddington SN, Mitrophanous KA, Ellard FM, Buckley SM, Nivsarkar M, Lawrence L, Cook HT, Al-Allaf F, Bigger B, Kingsman SM, Coutelle C, Themis M. Waddington SN, et al. Gene Ther. 2003 Aug;10(15):1234-40. doi: 10.1038/sj.gt.3301991. Gene Ther. 2003. PMID: 12858188

6

The hopes and fears of in utero gene therapy for genetic disease--a review.

Coutelle C, Themis M, Waddington S, Gregory L, Nivsarkar M, Buckley S, Cook T, Rodeck C, Peebles D, David A. Coutelle C, et al. Placenta. 2003 Oct;24 Suppl B:S114-21. doi: 10.1016/s0143-4004(03)00140-1. Placenta. 2003. PMID: 14559040 Review.

7

Widespread and efficient marker gene expression in the airway epithelia of fetal sheep after minimally invasive tracheal application of recombinant adenovirus in utero.

Peebles D, Gregory LG, David A, Themis M, Waddington SN, Knapton HJ, Miah M, Cook T, Lawrence L, Nivsarkar M, Rodeck C, Coutelle C. Peebles D, et al. Among authors: waddington sn. Gene Ther. 2004 Jan;11(1):70-8. doi: 10.1038/sj.gt.3302130. Gene Ther. 2004. PMID: 14681699

8

Reduced toxicity of F-deficient Sendai virus vector in the mouse fetus.

Waddington SN, Buckley SM, Bernloehr C, Bossow S, Ungerechts G, Cook T, Gregory L, Rahim A, Themis M, Neubert WJ, Coutelle C, Lauer UM, Bitzer M. Waddington SN, et al. Gene Ther. 2004 Apr;11(7):599-608. doi: 10.1038/sj.gt.3302205. Gene Ther. 2004. PMID: 14724676

9

Highly efficient EIAV-mediated in utero gene transfer and expression in the major muscle groups affected by Duchenne muscular dystrophy.

Gregory LG, Waddington SN, Holder MV, Mitrophanous KA, Buckley SM, Mosley KL, Bigger BW, Ellard FM, Walmsley LE, Lawrence L, Al-Allaf F, Kingsman S, Coutelle C, Themis M. Gregory LG, et al. Among authors: waddington sn. Gene Ther. 2004 Jul;11(14):1117-25. doi: 10.1038/sj.gt.3302268. Gene Ther. 2004. PMID: 15141156

10

Permanent phenotypic correction of hemophilia B in immunocompetent mice by prenatal gene therapy.

Waddington SN, Nivsarkar MS, Mistry AR, Buckley SM, Kemball-Cook G, Mosley KL, Mitrophanous K, Radcliffe P, Holder MV, Brittan M, Georgiadis A, Al-Allaf F, Bigger BW, Gregory LG, Cook HT, Ali RR, Thrasher A, Tuddenham EG, Themis M, Coutelle C. Waddington SN, et al. Blood. 2004 Nov 1;104(9):2714-21. doi: 10.1182/blood-2004-02-0627. Epub 2004 Jul 1. Blood. 2004. PMID: 15231566 Free article.

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