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An evaluation of the FDA responder endpoint for IBS-C clinical trials: analysis of data from linaclotide Phase 3 clinical trials.
Macdougall JE, Johnston JM, Lavins BJ, Nelson LM, Williams VS, Carson RT, Shiff SJ, Shi K, Kurtz CB, Baird MJ, Currie MG, Lembo AJ. Macdougall JE, et al. Among authors: currie mg. Neurogastroenterol Motil. 2013 Jun;25(6):481-6. doi: 10.1111/nmo.12089. Epub 2013 Feb 6. Neurogastroenterol Motil. 2013. PMID: 23384406 Clinical Trial.
Effect of 5 days linaclotide on transit and bowel function in females with constipation-predominant irritable bowel syndrome.
Andresen V, Camilleri M, Busciglio IA, Grudell A, Burton D, McKinzie S, Foxx-Orenstein A, Kurtz CB, Sharma V, Johnston JM, Currie MG, Zinsmeister AR. Andresen V, et al. Among authors: currie mg. Gastroenterology. 2007 Sep;133(3):761-8. doi: 10.1053/j.gastro.2007.06.067. Epub 2007 Jul 3. Gastroenterology. 2007. PMID: 17854590 Clinical Trial.
Efficacy of linaclotide for patients with chronic constipation.
Lembo AJ, Kurtz CB, Macdougall JE, Lavins BJ, Currie MG, Fitch DA, Jeglinski BI, Johnston JM. Lembo AJ, et al. Among authors: currie mg. Gastroenterology. 2010 Mar;138(3):886-95.e1. doi: 10.1053/j.gastro.2009.12.050. Epub 2010 Jan 4. Gastroenterology. 2010. PMID: 20045700 Clinical Trial.
Two randomized trials of linaclotide for chronic constipation.
Lembo AJ, Schneier HA, Shiff SJ, Kurtz CB, MacDougall JE, Jia XD, Shao JZ, Lavins BJ, Currie MG, Fitch DA, Jeglinski BI, Eng P, Fox SM, Johnston JM. Lembo AJ, et al. Among authors: currie mg. N Engl J Med. 2011 Aug 11;365(6):527-36. doi: 10.1056/NEJMoa1010863. N Engl J Med. 2011. PMID: 21830967 Free article. Clinical Trial.
Linaclotide for irritable bowel syndrome with constipation: a 26-week, randomized, double-blind, placebo-controlled trial to evaluate efficacy and safety.
Chey WD, Lembo AJ, Lavins BJ, Shiff SJ, Kurtz CB, Currie MG, MacDougall JE, Jia XD, Shao JZ, Fitch DA, Baird MJ, Schneier HA, Johnston JM. Chey WD, et al. Among authors: currie mg. Am J Gastroenterol. 2012 Nov;107(11):1702-12. doi: 10.1038/ajg.2012.254. Am J Gastroenterol. 2012. PMID: 22986437 Clinical Trial.
158 results