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Favipiravir (T-705), a novel viral RNA polymerase inhibitor.
Furuta Y, Gowen BB, Takahashi K, Shiraki K, Smee DF, Barnard DL. Furuta Y, et al. Among authors: takahashi k. Antiviral Res. 2013 Nov;100(2):446-54. doi: 10.1016/j.antiviral.2013.09.015. Epub 2013 Sep 29. Antiviral Res. 2013. PMID: 24084488 Free PMC article. Review.
Mechanism of action of T-705 against influenza virus.
Furuta Y, Takahashi K, Kuno-Maekawa M, Sangawa H, Uehara S, Kozaki K, Nomura N, Egawa H, Shiraki K. Furuta Y, et al. Among authors: takahashi k. Antimicrob Agents Chemother. 2005 Mar;49(3):981-6. doi: 10.1128/AAC.49.3.981-986.2005. Antimicrob Agents Chemother. 2005. PMID: 15728892 Free PMC article.
T-705 (favipiravir) activity against lethal H5N1 influenza A viruses.
Kiso M, Takahashi K, Sakai-Tagawa Y, Shinya K, Sakabe S, Le QM, Ozawa M, Furuta Y, Kawaoka Y. Kiso M, et al. Among authors: takahashi k. Proc Natl Acad Sci U S A. 2010 Jan 12;107(2):882-7. doi: 10.1073/pnas.0909603107. Epub 2009 Dec 22. Proc Natl Acad Sci U S A. 2010. PMID: 20080770 Free PMC article.
In vitro and in vivo activities of anti-influenza virus compound T-705.
Furuta Y, Takahashi K, Fukuda Y, Kuno M, Kamiyama T, Kozaki K, Nomura N, Egawa H, Minami S, Watanabe Y, Narita H, Shiraki K. Furuta Y, et al. Among authors: takahashi k. Antimicrob Agents Chemother. 2002 Apr;46(4):977-81. doi: 10.1128/AAC.46.4.977-981.2002. Antimicrob Agents Chemother. 2002. PMID: 11897578 Free PMC article.
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