Rummel A - Search Results

1

Structure of a bimodular botulinum neurotoxin complex provides insights into its oral toxicity.

Lee K, Gu S, Jin L, Le TT, Cheng LW, Strotmeier J, Kruel AM, Yao G, Perry K, Rummel A, Jin R. Lee K, et al. Among authors: rummel a. PLoS Pathog. 2013;9(10):e1003690. doi: 10.1371/journal.ppat.1003690. Epub 2013 Oct 10. PLoS Pathog. 2013. PMID: 24130488 Free PMC article.

2

Botulinum neurotoxin B recognizes its protein receptor with high affinity and specificity.

Jin R, Rummel A, Binz T, Brunger AT. Jin R, et al. Among authors: rummel a. Nature. 2006 Dec 21;444(7122):1092-5. doi: 10.1038/nature05387. Epub 2006 Dec 13. Nature. 2006. PMID: 17167421

3

Botulinum neurotoxin serotype D attacks neurons via two carbohydrate-binding sites in a ganglioside-dependent manner.

Strotmeier J, Lee K, Völker AK, Mahrhold S, Zong Y, Zeiser J, Zhou J, Pich A, Bigalke H, Binz T, Rummel A, Jin R. Strotmeier J, et al. Among authors: rummel a. Biochem J. 2010 Oct 15;431(2):207-16. doi: 10.1042/BJ20101042. Biochem J. 2010. PMID: 20704566

4

The biological activity of botulinum neurotoxin type C is dependent upon novel types of ganglioside binding sites.

Strotmeier J, Gu S, Jutzi S, Mahrhold S, Zhou J, Pich A, Eichner T, Bigalke H, Rummel A, Jin R, Binz T. Strotmeier J, et al. Among authors: rummel a. Mol Microbiol. 2011 Jul;81(1):143-56. doi: 10.1111/j.1365-2958.2011.07682.x. Epub 2011 Jun 2. Mol Microbiol. 2011. PMID: 21542861 Free article.

5

Human synaptotagmin-II is not a high affinity receptor for botulinum neurotoxin B and G: increased therapeutic dosage and immunogenicity.

Strotmeier J, Willjes G, Binz T, Rummel A. Strotmeier J, et al. Among authors: rummel a. FEBS Lett. 2012 Feb 17;586(4):310-3. doi: 10.1016/j.febslet.2011.12.037. Epub 2012 Jan 16. FEBS Lett. 2012. PMID: 22265973 Free article.

6

Botulinum neurotoxin is shielded by NTNHA in an interlocked complex.

Gu S, Rumpel S, Zhou J, Strotmeier J, Bigalke H, Perry K, Shoemaker CB, Rummel A, Jin R. Gu S, et al. Among authors: rummel a. Science. 2012 Feb 24;335(6071):977-81. doi: 10.1126/science.1214270. Science. 2012. PMID: 22363010 Free PMC article.

7

Identification of the SV2 protein receptor-binding site of botulinum neurotoxin type E.

Mahrhold S, Strotmeier J, Garcia-Rodriguez C, Lou J, Marks JD, Rummel A, Binz T. Mahrhold S, et al. Among authors: rummel a. Biochem J. 2013 Jul 1;453(1):37-47. doi: 10.1042/BJ20130391. Biochem J. 2013. PMID: 23621114

8

Botulinum neurotoxin G binds synaptotagmin-II in a mode similar to that of serotype B: tyrosine 1186 and lysine 1191 cause its lower affinity.

Willjes G, Mahrhold S, Strotmeier J, Eichner T, Rummel A, Binz T. Willjes G, et al. Among authors: rummel a. Biochemistry. 2013 Jun 4;52(22):3930-8. doi: 10.1021/bi4003502. Epub 2013 May 17. Biochemistry. 2013. PMID: 23647335

9

Substrates and controls for the quantitative detection of active botulinum neurotoxin in protease-containing samples.

Bagramyan K, Kaplan BE, Cheng LW, Strotmeier J, Rummel A, Kalkum M. Bagramyan K, et al. Among authors: rummel a. Anal Chem. 2013 Jun 4;85(11):5569-76. doi: 10.1021/ac4008418. Epub 2013 May 22. Anal Chem. 2013. PMID: 23656526 Free PMC article.

10

Exchanging the minimal cell binding fragments of tetanus neurotoxin in botulinum neurotoxin A and B impacts their toxicity at the neuromuscular junction and central neurons.

Höltje M, Schulze S, Strotmeier J, Mahrhold S, Richter K, Binz T, Bigalke H, Ahnert-Hilger G, Rummel A. Höltje M, et al. Among authors: rummel a. Toxicon. 2013 Dec 1;75:108-21. doi: 10.1016/j.toxicon.2013.06.010. Epub 2013 Jun 29. Toxicon. 2013. PMID: 23817019

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