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The genetic heterogeneity and mutational burden of engineered melanomas in zebrafish models.
Yen J, White RM, Wedge DC, Van Loo P, de Ridder J, Capper A, Richardson J, Jones D, Raine K, Watson IR, Wu CJ, Cheng J, Martincorena I, Nik-Zainal S, Mudie L, Moreau Y, Marshall J, Ramakrishna M, Tarpey P, Shlien A, Whitmore I, Gamble S, Latimer C, Langdon E, Kaufman C, Dovey M, Taylor A, Menzies A, McLaren S, O'Meara S, Butler A, Teague J, Lister J, Chin L, Campbell P, Adams DJ, Zon LI, Patton EE, Stemple DL, Futreal PA. Yen J, et al. Among authors: taylor a. Genome Biol. 2013;14(10):R113. doi: 10.1186/gb-2013-14-10-r113. Genome Biol. 2013. PMID: 24148783 Free PMC article.
Small molecule screening in zebrafish: swimming in potential drug therapies.
Tamplin OJ, White RM, Jing L, Kaufman CK, Lacadie SA, Li P, Taylor AM, Zon LI. Tamplin OJ, et al. Among authors: taylor am. Wiley Interdiscip Rev Dev Biol. 2012 May-Jun;1(3):459-68. doi: 10.1002/wdev.37. Epub 2012 Feb 28. Wiley Interdiscip Rev Dev Biol. 2012. PMID: 23801494 Free PMC article. Review.
Calmodulin inhibitors improve erythropoiesis in Diamond-Blackfan anemia.
Taylor AM, Macari ER, Chan IT, Blair MC, Doulatov S, Vo LT, Raiser DM, Siva K, Basak A, Pirouz M, Shah AN, McGrath K, Humphries JM, Stillman E, Alter BP, Calo E, Gregory RI, Sankaran VG, Flygare J, Ebert BL, Zhou Y, Daley GQ, Zon LI. Taylor AM, et al. Sci Transl Med. 2020 Oct 21;12(566):eabb5831. doi: 10.1126/scitranslmed.abb5831. Sci Transl Med. 2020. PMID: 33087503 Free PMC article.
Whole-exome sequencing and functional studies identify RPS29 as a novel gene mutated in multicase Diamond-Blackfan anemia families.
Mirabello L, Macari ER, Jessop L, Ellis SR, Myers T, Giri N, Taylor AM, McGrath KE, Humphries JM, Ballew BJ, Yeager M, Boland JF, He J, Hicks BD, Burdett L, Alter BP, Zon L, Savage SA. Mirabello L, et al. Among authors: taylor am. Blood. 2014 Jul 3;124(1):24-32. doi: 10.1182/blood-2013-11-540278. Epub 2014 May 14. Blood. 2014. PMID: 24829207 Free PMC article.
Drug discovery for Diamond-Blackfan anemia using reprogrammed hematopoietic progenitors.
Doulatov S, Vo LT, Macari ER, Wahlster L, Kinney MA, Taylor AM, Barragan J, Gupta M, McGrath K, Lee HY, Humphries JM, DeVine A, Narla A, Alter BP, Beggs AH, Agarwal S, Ebert BL, Gazda HT, Lodish HF, Sieff CA, Schlaeger TM, Zon LI, Daley GQ. Doulatov S, et al. Among authors: taylor am. Sci Transl Med. 2017 Feb 8;9(376):eaah5645. doi: 10.1126/scitranslmed.aah5645. Sci Transl Med. 2017. PMID: 28179501 Free PMC article.
Variability between human experts and artificial intelligence in identification of anatomical structures by ultrasound in regional anaesthesia: a framework for evaluation of assistive artificial intelligence.
Bowness JS, Morse R, Lewis O, Lloyd J, Burckett-St Laurent D, Bellew B, Macfarlane AJR, Pawa A, Taylor A, Noble JA, Higham H. Bowness JS, et al. Br J Anaesth. 2023 Oct 26:S0007-0912(23)00542-1. doi: 10.1016/j.bja.2023.09.023. Online ahead of print. Br J Anaesth. 2023. PMID: 39492288
Classification of Variants of Reduced Penetrance in High Penetrance Cancer Susceptibility Genes: Framework for Genetics Clinicians and Clinical Scientists by CanVIG-UK (Cancer Variant Interpretation Group-UK).
Garrett A, Allen S, Durkie M, Burghel GJ, Robinson R, Callaway A, Field J, Frugtniet B, Palmer-Smith S, Grant J, Pagan J, McDevitt T, Rowlands CF, McVeigh T, Hanson H, Turnbull C; CanVIG-UK. Garrett A, et al. Genet Med. 2024 Oct 24:101305. doi: 10.1016/j.gim.2024.101305. Online ahead of print. Genet Med. 2024. PMID: 39489894 Free article.
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