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The CD4-centered universe of human T cell subsets.
Geginat J, Paroni M, Facciotti F, Gruarin P, Kastirr I, Caprioli F, Pagani M, Abrignani S. Geginat J, et al. Among authors: pagani m. Semin Immunol. 2013 Nov 15;25(4):252-62. doi: 10.1016/j.smim.2013.10.012. Epub 2013 Nov 1. Semin Immunol. 2013. PMID: 24183700 Review.
IL-10 producing regulatory and helper T-cells in systemic lupus erythematosus.
Geginat J, Vasco M, Gerosa M, Tas SW, Pagani M, Grassi F, Flavell RA, Meroni P, Abrignani S. Geginat J, et al. Among authors: pagani m. Semin Immunol. 2019 Aug;44:101330. doi: 10.1016/j.smim.2019.101330. Epub 2019 Nov 15. Semin Immunol. 2019. PMID: 31735515 Free article. Review.
IL-21 is a central memory T cell-associated cytokine that inhibits the generation of pathogenic Th1/17 effector cells.
Kastirr I, Maglie S, Paroni M, Alfen JS, Nizzoli G, Sugliano E, Crosti MC, Moro M, Steckel B, Steinfelder S, Stölzel K, Romagnani C, Botti F, Caprioli F, Pagani M, Abrignani S, Geginat J. Kastirr I, et al. Among authors: pagani m. J Immunol. 2014 Oct 1;193(7):3322-31. doi: 10.4049/jimmunol.1400775. Epub 2014 Aug 29. J Immunol. 2014. PMID: 25172491 Clinical Trial.
Repression of miR-31 by BCL6 stabilizes the helper function of human follicular helper T cells.
Ripamonti A, Provasi E, Lorenzo M, De Simone M, Ranzani V, Vangelisti S, Curti S, Bonnal RJP, Pignataro L, Torretta S, Geginat J, Rossetti G, Pagani M, Abrignani S. Ripamonti A, et al. Among authors: pagani m. Proc Natl Acad Sci U S A. 2017 Nov 28;114(48):12797-12802. doi: 10.1073/pnas.1705364114. Epub 2017 Nov 13. Proc Natl Acad Sci U S A. 2017. PMID: 29133396 Free PMC article.
Evidence for a pathogenic role of extrafollicular, IL-10-producing CCR6+B helper T cells in systemic lupus erythematosus.
Facciotti F, Larghi P, Bosotti R, Vasco C, Gagliani N, Cordiglieri C, Mazzara S, Ranzani V, Rottoli E, Curti S, Penatti A, Karnani B, Kobayashi Y, Crosti M, Bombaci M, van Hamburg JP, Rossetti G, Gualtierotti R, Gerosa M, Gatti S, Torretta S, Pignataro L, Tas SW, Abrignani S, Pagani M, Grassi F, Meroni PL, Flavell RA, Geginat J. Facciotti F, et al. Among authors: pagani m. Proc Natl Acad Sci U S A. 2020 Mar 31;117(13):7305-7316. doi: 10.1073/pnas.1917834117. Epub 2020 Mar 17. Proc Natl Acad Sci U S A. 2020. PMID: 32184325 Free PMC article.
NS5A inhibitors impair NS5A-phosphatidylinositol 4-kinase IIIα complex formation and cause a decrease of phosphatidylinositol 4-phosphate and cholesterol levels in hepatitis C virus-associated membranes.
Reghellin V, Donnici L, Fenu S, Berno V, Calabrese V, Pagani M, Abrignani S, Peri F, De Francesco R, Neddermann P. Reghellin V, et al. Among authors: pagani m. Antimicrob Agents Chemother. 2014 Dec;58(12):7128-40. doi: 10.1128/AAC.03293-14. Epub 2014 Sep 15. Antimicrob Agents Chemother. 2014. PMID: 25224012 Free PMC article.
Epigenetic regulation by polycomb repressive complex 1 promotes cerebral cavernous malformations.
Pham VC, Rödel CJ, Valentino M, Malinverno M, Paolini A, Münch J, Pasquier C, Onyeogaziri FC, Lazovic B, Girard R, Koskimäki J, Hußmann M, Keith B, Jachimowicz D, Kohl F, Hagelkruys A, Penninger JM, Schulte-Merker S, Awad IA, Hicks R, Magnusson PU, Faurobert E, Pagani M, Abdelilah-Seyfried S. Pham VC, et al. Among authors: pagani m. EMBO Mol Med. 2024 Oct 14. doi: 10.1038/s44321-024-00152-9. Online ahead of print. EMBO Mol Med. 2024. PMID: 39402138 Free article.
841 results