Finkbeiner WE - Search Results

1

Anchored PDE4 regulates chloride conductance in wild-type and ΔF508-CFTR human airway epithelia.

Blanchard E, Zlock L, Lao A, Mika D, Namkung W, Xie M, Scheitrum C, Gruenert DC, Verkman AS, Finkbeiner WE, Conti M, Richter W. Blanchard E, et al. Among authors: finkbeiner we. FASEB J. 2014 Feb;28(2):791-801. doi: 10.1096/fj.13-240861. Epub 2013 Nov 7. FASEB J. 2014. PMID: 24200884 Free PMC article.

2

CFTR-adenylyl cyclase I association responsible for UTP activation of CFTR in well-differentiated primary human bronchial cell cultures.

Namkung W, Finkbeiner WE, Verkman AS. Namkung W, et al. Among authors: finkbeiner we. Mol Biol Cell. 2010 Aug 1;21(15):2639-48. doi: 10.1091/mbc.E09-12-1004. Epub 2010 Jun 16. Mol Biol Cell. 2010. PMID: 20554763 Free PMC article.

3

Hyperviscous airway periciliary and mucous liquid layers in cystic fibrosis measured by confocal fluorescence photobleaching.

Derichs N, Jin BJ, Song Y, Finkbeiner WE, Verkman AS. Derichs N, et al. Among authors: finkbeiner we. FASEB J. 2011 Jul;25(7):2325-32. doi: 10.1096/fj.10-179549. Epub 2011 Mar 22. FASEB J. 2011. PMID: 21427214 Free PMC article.

4

Cystic fibrosis and the relationship between mucin and chloride secretion by cultures of human airway gland mucous cells.

Finkbeiner WE, Zlock LT, Morikawa M, Lao AY, Dasari V, Widdicombe JH. Finkbeiner WE, et al. Am J Physiol Lung Cell Mol Physiol. 2011 Oct;301(4):L402-14. doi: 10.1152/ajplung.00210.2010. Epub 2011 Jul 1. Am J Physiol Lung Cell Mol Physiol. 2011. PMID: 21724859 Free PMC article.

5

Small-molecule activators of TMEM16A, a calcium-activated chloride channel, stimulate epithelial chloride secretion and intestinal contraction.

Namkung W, Yao Z, Finkbeiner WE, Verkman AS. Namkung W, et al. Among authors: finkbeiner we. FASEB J. 2011 Nov;25(11):4048-62. doi: 10.1096/fj.11-191627. Epub 2011 Aug 11. FASEB J. 2011. PMID: 21836025 Free PMC article.

6

Inhibitors of pendrin anion exchange identified in a small molecule screen increase airway surface liquid volume in cystic fibrosis.

Haggie PM, Phuan PW, Tan JA, Zlock L, Finkbeiner WE, Verkman AS. Haggie PM, et al. Among authors: finkbeiner we. FASEB J. 2016 Jun;30(6):2187-97. doi: 10.1096/fj.201600223R. Epub 2016 Mar 1. FASEB J. 2016. PMID: 26932931 Free PMC article.

Studies using pendrin knockout mice and airway epithelial cells from hearing-impaired subjects with pendrin loss of function suggest involvement of pendrin in inflammatory lung diseases, including cystic fibrosis (CF), perhaps by regulation of airway surface liquid (ASL) volume. …

Studies using pendrin knockout mice and airway epithelial cells from hearing-impaired subjects with pendrin loss of function suggest involve …

7

Submucosal gland dysfunction as a primary defect in cystic fibrosis.

Salinas D, Haggie PM, Thiagarajah JR, Song Y, Rosbe K, Finkbeiner WE, Nielson DW, Verkman AS. Salinas D, et al. Among authors: finkbeiner we. FASEB J. 2005 Mar;19(3):431-3. doi: 10.1096/fj.04-2879fje. Epub 2004 Dec 13. FASEB J. 2005. PMID: 15596485

8

In situ measurement of airway surface liquid [K+] using a ratioable K+-sensitive fluorescent dye.

Namkung W, Song Y, Mills AD, Padmawar P, Finkbeiner WE, Verkman AS. Namkung W, et al. Among authors: finkbeiner we. J Biol Chem. 2009 Jun 5;284(23):15916-26. doi: 10.1074/jbc.M808021200. Epub 2009 Apr 13. J Biol Chem. 2009. PMID: 19364771 Free PMC article.

9

Airway surface liquid depth measured in ex vivo fragments of pig and human trachea: dependence on Na+ and Cl- channel function.

Song Y, Namkung W, Nielson DW, Lee JW, Finkbeiner WE, Verkman AS. Song Y, et al. Among authors: finkbeiner we. Am J Physiol Lung Cell Mol Physiol. 2009 Dec;297(6):L1131-40. doi: 10.1152/ajplung.00085.2009. Epub 2009 Oct 9. Am J Physiol Lung Cell Mol Physiol. 2009. PMID: 19820035 Free PMC article.

10

Synergy-based small-molecule screen using a human lung epithelial cell line yields ΔF508-CFTR correctors that augment VX-809 maximal efficacy.

Phuan PW, Veit G, Tan J, Roldan A, Finkbeiner WE, Lukacs GL, Verkman AS. Phuan PW, et al. Among authors: finkbeiner we. Mol Pharmacol. 2014 Jul;86(1):42-51. doi: 10.1124/mol.114.092478. Epub 2014 Apr 15. Mol Pharmacol. 2014. PMID: 24737137 Free PMC article.

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